Immunological Aspect of Meningococcal disease: An overview in Host- Bacteria Interaction

International Journal of Molecular and Clinical Microbiology

مقاله 1، دوره 1، Issue 1، تیر 2011، صفحه 1-8   

نوع مقاله: Review

نویسندگان

Seyed Davar Siadat^{* 1}؛ Mohammad Reza Aghasadeghi²؛ Maryam Kheirandish³

¹Ph.D in Medical Microbiology- Associate Prof. of Hepatitis & AIDS and Bacterial Vaccines and Antigen Production Department , Pasteur Institute of Iran, Tehran, Iran

²Ph.D in Medical Biotechnology- Assistant Prof. of Hepatitis & AIDS Department, Pasteur Institute of Iran, Tehran, Iran

³Ph.D in Immunology- Assistant Prof. of Research Center of Iranian Blood Transfusion Organization, Tehran, Iran

چکیده

Meningococcal disease remains a significant global public health and is unique among causes of bacterial meningitis and sepsis where it not only causes sporadic disease but also outbreaks. Meningococcal disease has a rapid onset with high mortality. The understanding of immunopathogenesis is crucial for development of novel therapeutic strategies and vaccines designed against meningococcal disease. In this review, immunological aspects of meningococcal disease have been discussed and the immunopathogenesis of this disease is challenged.

کلیدواژه‌ها

Meningococcal Diseases؛ Immunopathogenesis؛ Bacterial Interaction