Determining the Frequency of Antibiotic Sensitivity in Blood Infections inn Ardabil province in 2010-2011

International Journal of Molecular and Clinical Microbiology

مقاله 4، دوره 2، شماره 1، مهر 2012، صفحه 128-133   

نوع مقاله: Research Article

نویسندگان

Elham Fargi¹؛ Alireza Jafari^{* 2}

¹Young Researchers Club, Ardabil Branch, Islamic Azad University, Ardebil, Iran

²Department of Microbiology, Islamic Azad University Ardabil Branch, Ardabil, Iran

چکیده

Determination of the frequency of bacteria isolated from blood culture and the pattern of their antibiotic sensitivity is epidemiologically of great importance and can help choosing primary antimicrobial treatment. The aim of the current study was to determine the most common bacterial factors of blood infection and their antibiotic sensitivity in a one year period from October 2010 till the end of September 2011 in Imam Khumeini hospital of Ardebil. Data collected from total of 1469 patients susceptible to blood infection hospitalized in Imam Khumeini hospital and analyzed using SPSS (version 18) statistical software and investigated with descriptive statistics and frequency diagrams. Only values with P≤0.05 were considered as significant. The highest rate of bacteremia prevalence observed in emergency unit. Of 1469 blood sample, 91 (6.19%) were infected with bacteria. Infection prevalence reported higher in male (55.4%) than to female (44.6%). The most common bacteria isolated were, Negative-coagulase Staphylococcus (37.3%), Escherichia coli (22%), Staphylococcus aureus (11%) and Staphylococcus epidermidis (11%), respectively. The highest antibiotic sensitivity was associated with Gentamicin with the frequency rate of 42 (51.3%) and Ciprofloxacin with the frequency rate of 35 (42.7%). Gentamicin and Ciprofloxacin determined as two completely effective antibiotics on isolated strains. Regarding the increased prevalence of infection with Negative-coagulase Staphylococcus in the current study and other similar studies, the morbidity and mortality rate of the disease can be decreased using proper antibiotic treatments complying with the exact results of the disc diffusion test method.

کلیدواژه‌ها

antibiotic sensitivity؛ Blood infections؛ Ardabil