Resistance Rates to Various Antimicrobial Agents of Helicobacter pylori Isolates in Eastern Turkey

International Journal of Molecular and Clinical Microbiology

مقاله 8، دوره 2، شماره 1، مهر 2012، صفحه 148-152   

نوع مقاله: Research Article

نویسندگان

Gokben Ozbey^{* 1}؛ Ibrahim Halil Bahcecioglu²؛ Mehmet Nuri Acik³

¹Vocational School of Health Services, Firat University, 23119, Elazig, Turkey

²Department of Gastroenterology, Faculty of Medicine, Firat University, 23119, Elazig, Turkey

³Vocational School of Health Services, Bingol University, 12000, Bingol, Turkey

چکیده

The aim of this study was to determine the resistance rates of Helicobacter pylori (H. pylori) to various antimicrobial agents. The agar disk diffusion method (Kirby Bauer) was used to determine the sensitivity of H. pylori isolates to various antimicrobials. Of the 61 H. pylori isolatestested, no isolates was resistant to amoxycillin and tetracycline. The resistance rates were 42.6% for metronidazole, 21.3% for clarithromycin, and 3.3% for levofloxacin. Compared to clarithromycin and metronidazole, levofloxacin showed the lowest resistance. This is the first report on the resistance rates of H. pylori to antibiotics in Elazig Province, East of Turkey. This study suggests that the large scale studies is needed to help us to understand better the effect of resistance on the H. pylori eradication.

کلیدواژه‌ها

Helicobacter pylori؛ Resistance؛ metronidazole؛ Clarithromycin