Retinoic Acid Determines the Fate of Spermatogonia

Iranian Journal of Applied Animal Science

مقاله 2، دوره 3، شماره 3، آذر 2013، صفحه 431-438   

نوع مقاله: Review Article

نویسندگان

A. Yilmaz^{* 1}؛ A. Ozdal Gokdal²

¹Department of Animal Science, Hizan Vocational School, Bitlis Eren University, TR 13000, Bitlis, Turkey

²Department of Plant and Animal Production, Cine Vocational School, Adnan Menderes University, TR 09500, Aydin, Turkey

چکیده

In this review, we aim to examine the effect of extrinsic and intrinsic factors on spermatogenesis process taking into account a complex signaling pathway. Primarily, it is suggested that retinoic acid (RA) has a vital function in spermatogenesis process and it is considered to be essential for completion of spermatogonia into mature spermatozoa. In the present review, the key effects of retinoic acid (RA) on spermatogenesis process were evaluated in the perspective of studies done, particularly at molecular level. Thus, this review will provide re look the spermatogenesis process in an outlook of new studies.

کلیدواژه‌ها

retinoic acid؛ Spermatogenesis؛ spermatogonia؛ Testis

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