Synthesis of new 1,3-thiazoline-2-thiones as potential antimycobacterial agents

Journal of Pharmaceutical & Health Sciences

مقاله 17، دوره 1، شماره 3، شهریور 2013، صفحه 137-142   

نوع مقاله: Original Article

چکیده

As a continuation of our efforts in developing new antimycobacterial agents, a series of new 1,3-thiazolidine-2-thione derivatives were synthesized. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR and Mass spectra. The analysis of theoretical toxicity risks,drug-likeness and drug-score for these series using Osiris program showed acceptable results.

کلیدواژه‌ها

Tuberculosis؛ Mycobacterium؛ 1؛ 3-thiazolidine-2-thione