Caro’sacid-silicagel: An Efficient and Reusable Catalyst for the Synthesis of 2, 4, 5- Trisubstituted Imidazoles under Solvent-free Conditions

Journal of Applied Chemical Research

مقاله 6، دوره 8، شماره 2، مرداد 2014، صفحه 53-59   

نوع مقاله: Research Paper

نویسندگان

Khalil Pourshamsian؛ Naser Montazeri؛ Sadegh Asadyan^*

چکیده

Caro’s acid-silicagel was found to be a mild and effective catalyst for the one –pot multicomponent condensation of benzyl, aldehydes and ammonium acetate used for synthesis of 2, 4, 5-trisubstituted imidazole derivatives under solvent–free conditions. This catalyst has several advantages such as simple work-up, low cost and reusability.

کلیدواژه‌ها

Caro’s acid-silicagel؛ 2؛ 4؛ 5 –Tri substituted imidazoles؛ Multicomponent reactions