An Improved Process for the Production of 5-Methyl-1,2,4-triazolo(3,4-b) benzothiazole as a Fungicide

Journal of Applied Chemical Research

مقاله 9، دوره 8، شماره 2، مرداد 2014، صفحه 77-81   

نوع مقاله: Research Paper

نویسندگان

Abbas Ahmadi^* ؛ Babak Nahri-Niknafs

چکیده

In this study an improved process for the production of 5-Methyl-1,2,4-triazolo(3,4-b) benzothiazole fungicide (IV) is described. Firstly, (2-methylphenyl) thiourea (I), 2-amino- 4-methylbenzothiazole (II) and 2-hydrazino-4-methylbenzothiazole (III) as intermediates consequently were prepared. Then IV is synthesized by the reaction of III with formic acid in the presence of p-toluenesulfonic acid catalyst. The purity of the synthesized compounds was confirmed by CHN analysis and the structures verified on the basis of IR, 1 H-NMR and mass spectral data.

کلیدواژه‌ها

2-amino-4-methylbenzothiazole؛ 2-hydrazino-4-methylbenzothiazole؛ (2-methylphenyl)thiourea؛ Benzothiazoles؛ fungicide