A One-Pot Synthesis of Highly Functionalized Ketenimines by a Three-component 2-Thioxothiazolidin-4-one, Alkyl Isocyanides and Dialkyl Acetylenedicarboxylates

Journal of Applied Chemical Research

مقاله 5، دوره 10، شماره 1، فروردین 2016، صفحه 49-55   

نوع مقاله: Research Paper

نویسنده

Khadijeh Yadollahzadeh

چکیده

The 1:1 reactive intermediates produced in the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates were trapped with 2-thioxothiazolidin-4-one to generate to highly functionalized ketenimines. A series of new 2-thioxothiazolidin-4-one derivatives were synthesized in moderate yields. The advantages of the present method include good functional group tolerance and simple experimental procedure and purification

کلیدواژه‌ها

Ketenimines؛ 2-Thioxothiazolidin-4-one؛ Acetylenic esters؛ Isocyanides