THE ROLE OF TREATMENT ON CONTROLLING CHANCROID PREVALENCE

International Journal of Mathematical Modelling & Computations

مقاله 1، دوره 1، 3 (SUMMER)، فروردین 2011، صفحه 159-170   

نویسندگان

S. Mushayabasa¹؛ C. P. Bhunu²

¹Modelling Biomedical Systems Research Group, National University of Science and Technology, Box AC 939 Ascot, Bulawayo Zimbabwe Department of Applied Mathematics

²University of Zimbabwe, Box MP 167 Mount Pleasant, Harare Zimbabwe Department of Applied Mathematics

چکیده

Chancroid is a highly infectious and curable sexually transmitted disease caused by the bacterium Haemophilus Ducreyl (also known as H. Ducreyl). A deterministic mathematical model for investigating the role of treatment on controlling chancroid epidemic is formulated and rigorously analyzed. A threshold quantity known as the productive number, which measures the number of secondary infections produced by a single chancroid infective when introduced in a population of susceptible in the presence of treatment has been derived. Equilibria for the model are determined and their stability are examined. Latin hypercube sampling has been used to perform the sensitivity analysis of the reproductive number.

کلیدواژه‌ها

Chancroid؛ Treatment؛ reproductive number؛ Stability؛ Sensitivity analysis