Reaction between 3-hydroxy pyridine alkyl isocyanides and dialkyl acetylenedicarboxylate: synthesis of 4H-chromenes

Journal of Chemical Reactivity and Synthesis

مقاله 7، دوره 1، شماره 1، مرداد 2011، صفحه 47-50   

نوع مقاله: Research Article

نویسندگان

Mahsa Mahpeyma^* ؛ Bita Mohtat

Department of Organic Chemistry, Karaj Branch, Islamic Azad university, Karaj, Iran

چکیده

The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide and cyclohexyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 3-hydroxy pyridine to produce highly functionalized 4H-chromenes in fairly good  yields.

کلیدواژه‌ها

3-hydroxy pyridine؛ dialkyl acetylene dicarboxylates؛ Alkyl isocyanide؛ multi component reaction؛ 4H-chromenes