Microwave-assisted Synthesis of Nـ alkyl 2ـ ketomethyl quinoline Derivatives Under Solvent-free Conditions

Journal of Chemical Reactivity and Synthesis

مقاله 6، دوره 1، شماره 2، مرداد 2011، صفحه 35-42   

نوع مقاله: Research Article

نویسندگان

Javad Safari^{* 1}؛ Hassan Karbasizadeh²؛ Sayed Hossein Banitaba³

¹Laboratory of Organic Chemistry Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, Kashan, I.R. Iran.

²Laboratory of Organic Chemistry Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, Kashan, I.R. Iran

³Laboratory of Organic Chemistry Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, Kashan, I.R. Iran.

چکیده

A series of Nـ alkyl 2ـ ketomethylquinoline derivatives were synthesis by reaction of benzoyl chloride derivatives with Nـ methyl quinaldine iodide in the presence of triethyl amine under microwave irradiation. Enaminone form of the product study by spectroscopy method. The result revealed the  Nـ alkyl 2ـ ketomethylquinoline the fixed enaminone tautomer.

کلیدواژه‌ها

Nـ alkyl 2ـ ketomethylquinoline؛ Enaminone؛ triethyl amine؛ Microwave irradiation؛ Solvent-free conditions