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Biginelli Synthesis and Theoritical Study of Dihydropyrimidinone Compounds | ||
| Journal of Chemical Reactivity and Synthesis | ||
| مقاله 4، دوره 2، شماره 3، مرداد 2012، صفحه 28-34 اصل مقاله (246.17 K) | ||
| نوع مقاله: Research Article | ||
| نویسندگان | ||
| Mohammad Hosein Farjam* 1؛ Ramin Rezaei2 | ||
| 1Department of Chemistry , Firoozabad Branch, Islamic Azad University,Firoozabad, Iran | ||
| 2Department of Chemistry , Firoozabad Branch, Islamic Azad University, Firoozabad, Iran | ||
| چکیده | ||
| An effective one-pot synthesis of dihydropyrimidinonoes in solvent free conditions using CuCl2 as an inexpensive and readily available reagent through Biginelli condensation reaction of aldehyde derivatives, 1,3-dicarbonyl compounds and urea is described. Excellent yields, short reaction times for formation of the products and simple work-up are attractive features of this green protocol. | ||
| کلیدواژه‌ها | ||
| Biginelli reaction؛ Dihydropyrimidinones؛ One-pot؛ Solvent-free | ||
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آمار تعداد مشاهده مقاله: 273 تعداد دریافت فایل اصل مقاله: 672 |
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