New and Efficient Rout for One Pot Synthesis of acenaphtho[1,2-b] quinoxalines

Journal of Chemical Reactivity and Synthesis

مقاله 4، دوره 4، شماره 1، شهریور 2014، صفحه 55-65   

نوع مقاله: Research Article

نویسنده

Zahra Haghighi ju^*

Department of Medicinal Chemistry , Mazandaran University of Medical Sciences , Sary, Iran

چکیده

Acenaphtho derivatives have been reported as antitumor agents. So, the reaction of acenaphthylene-1,2-dione with 3,4-diaminobenzenethiol, and then with the alkyl chloride derivatives for the synthesis of acenaphtho [1,2-b] quinoxalines are reviewed. Excellent yields of the products, short reaction times and simple work-up are attractive features of this suitable protocol.

کلیدواژه‌ها

Synthesis؛ Acenaphthene-1,2-dione؛ pyrimidine , quinoxalines

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