Analog kefir production with a low phenylalanine for Phenylketonuria

Journal of Pharmaceutical & Health Sciences

مقاله 2، دوره 5، شماره 2، شهریور 2017، صفحه 111-120   

نوع مقاله: Original Article

نویسندگان

Amir Yari¹؛ Yousef Ramezan^{* 2}

¹Department of Food Sciences & Technology, Faculty of Advanced Sciences & Technology, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran.

²Department of Food Sciences & Technology, Faculty of Advanced Sciences & Technology, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran.

چکیده

Phenylketonuria (PKU) is one of the most prevalent types of hereditary metabolic disorders which is caused due to an absence or reduction of the activity of the Phenylalanine hydroxylase enzyme in the liver which in turn, inhibits the transformation of phenylalanine (Phe) to tyrosine. In clinical terms, this disorder is displayed with severe, permanent and irreversible mental retardation. This research was aimed at development of a highly nutrient and acceptable suitable analogue Kefir drink for these patients. The mentioned drink is based on milk permeate, cream powder and includes glycomacropeptide (GMP) as a source of protein, starter as a fermentation source, the trance glutamines (TG) enzyme, dough stabilizer and modified corn starch as tissue maker, salt and water. The GMP used in this analogue drink is intended for enrichment of the product and therefore it was added by 3% to one formula. The aforementioned sample had a lower calculated amount of pH and alcohol percentage in comparison with the 16 samples which did not have GMP. The results of this study showed that the analog kefir has a low level of phenylalanine (30.40 mg/100g) and in that regard, it can be considered to be useful for patients with PKU.

کلیدواژه‌ها

Permeate؛ Analogue kefir؛ Glycomacropeptide؛ Phenylketonuria؛ phenylalanine

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JPHS V5 I2 a2.pdf

JPHS V5 I2 a2.pdf

JPHS V5 I2 a2.pdf

JPHS V5 I2 a2.pdf

JPHS V5 I2 a2.pdf