Tannic acid: A Green Catalyst for the Eco-friendly Synthesis of 2,3-dihydroquinazolin-4(1H)-ones under Solvent Free Conditions

Journal of Applied Chemical Research

مقاله 4، دوره 11، شماره 4، دی 2017، صفحه 38-45   

نوع مقاله: Research Paper

نویسندگان

Mahdim Narouei¹؛ Nourallah Hazeri^{* 2}؛ Ebrahim Molashahi²؛ Sara Zhaleh²؛ Maryam Fatahpour²

¹Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran

²Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan,Iran

چکیده

A new, facile, cost effective, and eco-friendly protocol is reported for the synthesis of 2,3-
dihydroquinazoline-4-(1H)-ones exploring tannic acid as a novel, inexpensive, and
biodegradable catalyst. A variety of dihydroquinazolins were prepared from aromatic aldehydes
and anthranilamide using catalytic amount of tannic acid under solvent free conditions.
Operational simplicity, high yield, and high atom-economy are the important features of this
protocol.

کلیدواژه‌ها

2؛ 3-dihydroquinazoline-4-(1H)-ones؛ tannic acid؛ Solvent free conditions؛ Ecofriendly protocol