Sclerorhachis Platyrachis (Boiss.) Podlech Ex Rech. F.: an Indigenous Medicinal Plant from Northeastern Iran; Essential Oil Composition, Total Flavonoid Content and Antioxidant Activity

Journal of Chemical Health Risks

مقاله 5، دوره 5، شماره 2، مهر 2015   

شناسه دیجیتال (DOI): 10.22034/jchr.2015.544100

نویسندگان

Hashem Akhlaghi^{* 1}؛ Sedighe Sadat Akhlaghi²؛ Bhnam Mahdavi³؛ Hasan Rezaei⁴

¹Department of Basic Sciences, Sabzevar Branch, Islamic Azad University, Sabzevar, Iran

²Internist Department of Nephrology, Shahid Beheshti Medical University, Tehran, Iran

³Department of Chemistry, Hakim Sabzevari University, Sabzevar, Iran

⁴Traditional Medicine Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran

چکیده

: In this study, the essential oil obtained by hydrodistillation of the aerial parts of Sclerorhachis platyrachis (Boiss.) Podlech ex Rech. f. (Compositae), growing wild in Sabzevar, Khorasan Razavi Province (Iran), was analyzed by GC and GC/MS. The total yield of volatiles was 0.38% (w/w). Sixty- three compounds representing 89.2% of the aerial parts oil were identified.  The main components of the oil were β-pinene (17.5%) and γ-terpinene (15.4%). The oil was rich in monoterpenoids, and among them, monoterpene hydrocarbons (48.7%) predominated over oxygenated monoterpenes (11.8%). The total flavonoid content of different extracts of the plant was in the range 52.4-172.3 mg/g, with the maximum amount being in the methanol extract. The antioxidant activities of the extracts were also measured based on radical scavenging activity of antioxidants using the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) method. The results showed that IC50 values of extracts of S. platyrachisare higher than for the standard synthetic antioxidants, BHT, ascorbic acid and gallic acid.   

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