Condensation of thiohydrazide analogues with 4-bromo-3, 6-dichloropyridazine: an efficient rout to pyridazino[4, 3-e][1, 3, 4] thiadiazines

Journal of Chemical Reactivity and Synthesis

مقاله 1، دوره 8، شماره 1، خرداد 2018، صفحه 1-9   

نوع مقاله: Research Article

نویسندگان

Mohsen Nikpour^* ؛ Mahsa S alehpoor Kiani

Department of Chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz 6134968875, Iran.

چکیده

Abstract- Some new 3-(alkylsulfanyl)- 7-chloro-1-phenyl-1H-pyridazino [4,3-e][1,3,4]thiadiazine were synthesized  by treatment of the alkyl-2-phenylhydrazinecarbodithioates with 4-bromo-3,6-dichloropyridazine in alkaline acetonitril. Orientation of the reaction has been determined by X-Ray crystallography technique. The chlorine atom on the number 7 position of these products was replaced by secondary amines in reflux condition.