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A Novel protocol for synthesis of Hantzsch 1, 4- dihydropyridines using PEG-400 as a reaction medium and under catalyst-free condition | ||
Journal of Chemical Reactivity and Synthesis | ||
مقاله 2، دوره 8، شماره 3، آذر 2018، صفحه 5-11 اصل مقاله (486.98 K) | ||
نوع مقاله: Research Article | ||
نویسندگان | ||
Ali Ezabadi* 1؛ Fatemeh Tosan2 | ||
1Department of Chemistry, Faculty of Sciences, Islamic Azad University, Central Tehran Branch, Iran | ||
2Department of Chemistry, Faculty of Sciences, Islamic Azad University, Central Tehran Branch, Iran | ||
چکیده | ||
An efficient and expeditious catalyst-free procedure was developed for the one- pot synthesis of 1, 4-dihydropyridine derivatives via the three-component reaction of various aldehydes, ethyl acetoacetate, and ammonium acetate in PEG-400. The reaction was carried out at 110°С and the products were obtained in good to high yields. | ||
آمار تعداد مشاهده مقاله: 106 تعداد دریافت فایل اصل مقاله: 238 |