Investigation into the regioisomeric composition of some fused tetrazoles

Journal of Chemical Reactivity and Synthesis

مقاله 6، دوره 8، شماره 3، آذر 2018، صفحه 33-40   

نوع مقاله: Research Article

نویسندگان

Paria Nasehi؛ Omid Baravaye

Departmentof Chemistry, School of Sciences, Islamic Azad University, Ahvaz Branch, Ahvaz, 6134968875, Iran.

چکیده

Treatment of 7-chloro-1-phenylpyrimido[4,5-e][1,3,4]thiadiazines with hydrazine in boiling ethanol gave corresponding7-hydrazinyl derivatives. Diazotization of the latter compounds acheived a mixture of 5H-tetrazolo[1',5':1,2]pyrimido[4,5-e][1,3,4]thiadiazine and 9H-tetrazolo[5',1':2,3]pyrimido[4,5-e][1,3,4]thiadiazines. Ratio of these two group of products determined by ¹HNMR studies and no significant preference was observed for their formation. Efforts for separation of the products were unsuccessful and its reason is discussed.