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One-Pot Synthesis of Phenytoin Analogs in Solvent free Conditions Via the Use of Pestle/ Mortar | ||
| Journal of Chemical Reactivity and Synthesis | ||
| مقاله 4، دوره 8، شماره 4، بهمن 2018، صفحه 33-37 اصل مقاله (250.84 K) | ||
| نوع مقاله: Research Article | ||
| نویسنده | ||
| Alireza Kiasat | ||
| Department of Chemistry , Shahid Chamran University , Ahwaz , Iran | ||
| چکیده | ||
| phenytoine derivatives were synthesized , via the pinacol condensation with the reaction of 1,3- diphenyl- propane- 1,3- dione (benzyl) analogs with urea or thiourea in presence of slica gel and solid KOH as Solid phase catalyst in the mortar / pestle at room temperatures. The reaction was completed at short reaction times (approximately 15min) and pure products were obtained with high yields (81-94%). | ||
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آمار تعداد مشاهده مقاله: 165 تعداد دریافت فایل اصل مقاله: 142 |
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