Fabrication, Characterization and Osteoblast Response of Cobalt-Based Alloy/Nano Bioactive Glass Composites

Journal of Advanced Materials and Processing

مقاله 2، دوره 4، شماره 3، آذر 2016، صفحه 3-13   

نوع مقاله: Research Paper

نویسندگان

Mohammad Reza Bafandeh^{* 1}؛ Raziyeh Gharahkhani²؛ Mohammad Hossein Fathi²

¹Department of Materials Science and Engineering, Faculty of Engineering, University of Kashan, Kashan, I.R. Iran

²Department of Materials Engineering, Isfahan University of Technology (IUT), Isfahan 84156-83111, Iran

چکیده

IIn this work, cobalt-based alloy/ nano bioactive glass (NBG) composites with 10, 15 and 20 wt% NBG were prepared and their bioactivity after immersion in simulated body fluid (SBF) for 1 to 4 weeks was studied. The scanning electron microscopy images of two- step sintered composites revealed a relatively dense microstructure the density of which decreased with the increase in the NBG amount. Microstructural analysis as well as energy dispersive X-ray analysis (EDX) revealed that after 1 week of immersion in SBF, a small amount of calcium phosphate phases precipitates on the surface of the composite samples. After 2 weeks of immersion, a considerable amount of cauliflower-like shaped precipitations was observed on the surface of composites. The observed peaks in the Fourier transform infrared (FTIR) spectroscopy of the composite samples in SBF immersed for 4 weeks were assigned to hydroxyapatite. Therefore, a hydroxyapatite layer has been possibly formed on the surface of the composite samples during immersion in SBF. Cell culture results indicate that unlike the Co-based alloy, the Co-based/NBG composites are bioactive and bone cells could be vivid and grow on their surfaces, promising their possibility for implant applications.

کلیدواژه‌ها

Biomaterials؛ Sintering؛ Nano bioactive glass Response Surface؛ Osteoblast response

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