Antifungal activity of silver nanoparticles on some of fungi

International Journal of Nano Dimension

مقاله 7، دوره 1، شماره 3، خرداد 2011، صفحه 233-239   

نوع مقاله: Reasearch Paper

شناسه دیجیتال (DOI): 10.7508/ijnd.2010.03.007

نویسندگان

A. Nasrollahi^{* 1}؛ Kh. Pourshamsian²؛ P. Mansourkiaee³

¹Department of biology, Faculty of science, Islamic azad university, Tonekabon branch, Tonekabon, Iran.

²Department of chemistry, Faculty of science, Islamic azad university, Tonekabon branch, Tonekabon, Iran.

³Basic science student, Member of young researchers club, Islamic azad university of Tonekabon, Iran.

چکیده

In this study, we investigated the antifungal effects of silver nanoparticles (Ag-Nps) on Candida albicans (ATCC 5027), Saccharomyces cerevisiae (ATCC 5027). Investigating method by using Minimum Inhibitory Concentration (MIC) technique, some of drugs including Amphotericin B, Fluconazole and synthesized Ag-Nps have been obtained on the fungi and the changes on membrane reactions of yeasts have been elucidated by Scanning Electron Microscopy (SEM). The present study indicates Ag-Nps has considerable antifungal activity comparison with other antifungal drugs, so deserving further investigation for clinical applications.

کلیدواژه‌ها

Silvernanoparticles (Ag-Nps)؛ Antifungal activity؛ Minimum inhibitory concentration (MIC)