α-Amylase inhibition and antioxidant activity of Singhnad Guggul in vitro

Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)

مقاله 1، دوره 4، شماره 2، مهر 2013، صفحه 59-62   

نوع مقاله: Short communication

نویسندگان

Ashok Kumar B.S^{* 1}؛ Saleemulla Khan²؛ Gopi Setty Saran¹؛ Naveen Kumar¹؛ Lokanath V¹

¹Department of Pharmacognosy, Sri K.V. College of Pharmacy, Chickballapur, Karnataka;

²Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India;

چکیده

Background & Aim: Singhnad Guggulu is a traditional Ayurvedic formula for detoxifying and rejuvenating the joints. The present study was to investigate the α-amylase inhibition and antioxidant activities of aqueous extract of Singhnad Guggul (AESG). Experimental: α-Amylase inhibition assay by dinitro-salicylic acid method and antioxidant activity by ferric chelating and ferrous reducing assay. Results: AESG indicated that potent α-amylase inhibition activity (IC₅₀= 84.00 µg/ml). AESG also showed ferric chelating and ferrous reducing activities. Recommended applications/industries: Our studies showed that  Singhnad Guggulu possess alpha- amylase and antioxidant properties.

کلیدواژه‌ها

Singhnad Guggul؛ α-amylase؛ Chelating assay

مراجع

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