ZnO-NPs as an efficient reusable heterogeneous catalyst for synthesis of 1,4-Dihydropyrimidine derivatives in solvent-free conditions

International Journal of Nano Dimension

مقاله 14، دوره 6، Issue 1، فروردین 2015، صفحه 99-104   

نوع مقاله: Reasearch Paper

شناسه دیجیتال (DOI): 10.7508/ijnd.2015.06.013

نویسنده

Kh. Pourshamsian^*

Department of Chemistry, Tonekabon branch, Islamic Azad University, Tonekabon, Iran.

چکیده

An efficient synthesis route to 1,4-dihydropyrimidine derivatives from reaction of divergent aldehydes with ethylacetoacetate and urea under solvent-free conditions by ZnO nanoparticles as a relative in expansive, eco-friendly, easy available, non-volatile, non-explosion, thermally robust, recyclable and easy to handle catalyst at 90°C with excellent yields is described. Unenhanced reaction times, simple reaction protocol and work-up, have been improved synthesis of these materials in the presence of this heterogeneous catalyst.

کلیدواژه‌ها

1,4-Dihydropyrimidinones؛ ZnO Nanoparticles؛ Solvent-free conditions؛ Heterogeneous catalyst؛ H-NMR