Response surface strategy in the synthesis of Fe3O4 nanoparticles

International Journal of Nano Dimension

مقاله 2، دوره 5، Issue 5، بهمن 2014، صفحه 421-430   

نوع مقاله: Reasearch Paper

شناسه دیجیتال (DOI): 10.7508/ijnd.2014.05.001

نویسندگان

N. Khalighyan¹؛ N. Hooshmand¹؛ N. Razzaghi-Asl²؛ K. Zare³؛ R. Miri^{* 2}

¹Department of Chemistry, Marvdasht branch, Islamic Azad University, Marvdasht, Iran.

²Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

³Chemistry Department, Shahid Beheshti University, Tehran, Evin, Iran.

چکیده

In the present study, Fe₃O₄ super paramagnetic nanoparticles were synthesized via co-precipitation of Fe³⁺ and Fe²⁺ chloride salts in the presence of ammonia Solution. The product was characterized by Fourier Transform Infrared spectroscopy (FT-IR), Transmission Electron Microscopy (TEM), and zeta–potential particle size distributing methods. The synthetic procedure of nano iron oxides were optimized using modern statistical optimization methods. A major bottleneck of common optimization protocols is the variation of just one factor at each trial. In modern optimization protocols (experimental design) a combination of factor levels is considered. In the present study, response surface method (RSM) was applied to optimize the synthetic approach towards Fe₃O₄ nanoparticles. Results indicated the importance of acidity and ferric ion amount in achieving desired Fe₃O₄ nanoparticles.

کلیدواژه‌ها

Synthesis؛ Nanoparticle؛ Fe3O4؛ Optimization؛ Experimental Disign