Main ingredients in herbal formulation may act as preservative agent

Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)

مقاله 7، دوره 8، شماره 2، آبان 2017، صفحه 116-120   

نوع مقاله: Original article

شناسه دیجیتال (DOI): 10.18869/JHD.2017.116

نویسندگان

Mohaddese Mahboubi^{* 1}؛ Maryam Memar Kermani¹؛ Hasan Karbasi Zadeh²

¹Microbiology Department, Medicinal Plant Research Center of Barij, Kashan, Iran

²Formulation Department, Medicinal Plant Research Center of Barij, Kashan, Iran

چکیده

Background & Aim:Nowadays, the use of chemical preservatives has been limited due to the controversial adverse effects. In this study, we evaluated the preservative potency of product with active herbal ingredients (Barij Baby cream) in contrast with the same products with two different chemical preservatives including methylparaben plus propylparaben and potassium sorbate plus sodium benzoate.
Experimental: The efficacy of herbal formulation against pathogens (E. coli, P. aeruginosa, C. albicans, A. niger, S. aureus) was evaluated by antimicrobial effectiveness test during 28 days.
Results: 2 log reductions in bacterial counts at 14 days from the initial count, and no growth in bacterial and fungal (molds and yeasts) counts at 28 days from the 14 days is essential for accepting the antimicrobial effectiveness of category 2 products in United States Pharmcopia (USP). Our results of antimicrobial effectiveness test showed that the active herbal ingredients in Barij Baby cream passed the USP criteria as chemical preservatives in the same product.
Recommended applications/industries: Therefore, in designing new herbal products, it is essential to evaluate the antimicrobial effectiveness of products before supplemented the product with chemical preservatives.

کلیدواژه‌ها

Barij Baby Cream؛ Antimicrobial effectiveness test؛ Natural preservative

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