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One-pot Synthesis of Amidoalkyl Naphthol Derivatives as Potential Nucleoside Antibiotics and HIV Protease Inhibitors using Nano-SnO2 as an Efficient Catalyst | ||
| Journal of Applied Chemical Research | ||
| دوره 14، شماره 4، دی 2021، صفحه 22-30 اصل مقاله (585.8 K) | ||
| نوع مقاله: Research Paper | ||
| نویسندگان | ||
| Bita Baghernejad* ؛ Elham Ashoori* | ||
| Department of Chemistry, Payame Noor University, Iran | ||
| چکیده | ||
| An efficient three-component one-pot synthesis of 1-amidoalkyl-2-naphthols from 2-naphthol, aldehydes, and acetamide using nano-SnO2as catalyst is described. The reactions were carried out at 80oC under water-solvent media. The structures of the compounds were characterized by IR, 1HNMR, 13C-NMR, and Mass spectra and by elemental analysis. The advantages of the effective method were good yields, short reaction times, simple work-up, eco-friendly solvent, and inexpensive and reusable catalyst. The catalyst could be recycled and reused for five times without much loss in its activity. | ||
| کلیدواژهها | ||
| Amidoalkyl Naphthols؛ Multicomponent reactions (MCRs)؛ One-pot synthesis؛ NanoSnO2؛ Eco-friendly solvent | ||
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آمار تعداد مشاهده مقاله: 331 تعداد دریافت فایل اصل مقاله: 366 |
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