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One-pot Synthesis of Amidoalkyl Naphthol Derivatives as Potential Nucleoside Antibiotics and HIV Protease Inhibitors using Nano-SnO2 as an Efficient Catalyst | ||
Journal of Applied Chemical Research | ||
دوره 14، شماره 4، دی 2021، صفحه 22-30 اصل مقاله (585.8 K) | ||
نوع مقاله: Research Paper | ||
نویسندگان | ||
Bita Baghernejad* ؛ Elham Ashoori* | ||
Department of Chemistry, Payame Noor University, Iran | ||
چکیده | ||
An efficient three-component one-pot synthesis of 1-amidoalkyl-2-naphthols from 2-naphthol, aldehydes, and acetamide using nano-SnO2as catalyst is described. The reactions were carried out at 80oC under water-solvent media. The structures of the compounds were characterized by IR, 1HNMR, 13C-NMR, and Mass spectra and by elemental analysis. The advantages of the effective method were good yields, short reaction times, simple work-up, eco-friendly solvent, and inexpensive and reusable catalyst. The catalyst could be recycled and reused for five times without much loss in its activity. | ||
کلیدواژهها | ||
Amidoalkyl Naphthols؛ Multicomponent reactions (MCRs)؛ One-pot synthesis؛ NanoSnO2؛ Eco-friendly solvent | ||
آمار تعداد مشاهده مقاله: 325 تعداد دریافت فایل اصل مقاله: 287 |