Salicylic acid an efficient organocatalyst for synthesis of coumarins

Journal of Chemical Reactivity and Synthesis

دوره 9، شماره 2، شهریور 2019، صفحه 38-48   

نوع مقاله: Research Article

نویسندگان

Rushikesh Mane؛ Pramod Kulkarnia^*

Post graduate center in Organic Chemistry and Department of Chemistry Hutatma Rajguru Mahavidyalaya, Rajgurunagar, Pune-410505 India

چکیده

Various substituted coumarins were synthesized in high yield and purity by direct reaction of substituted phenol and β-keto esters in the presence of a catalytic amount of salicylic acid under solvent-free conditions. This method is simple, cost-effective, short reaction time, simple work-up procedure, and avoid the use of transition metals.

کلیدواژه‌ها

Coumarins؛ Pechmann condensation؛ β-Keto esters؛ Phenol؛ Organocatalysis