تأثیر چهار هفته مصرف اسانس لیمو و تمرین شنا بر میزان حافظه و درد در موش‌های سوری نر بالغ

فصلنامه زیست شناسی جانوری

دوره 13، شماره 4، شهریور 1400، صفحه 1-13   

نوع مقاله: مقالات پژوهشی

نویسندگان

سارا احمدی زاده¹؛ عبدالحسن دولاح^{* 2}؛ مریم رفیعی راد³

¹گروه تربیت بدنی و علوم ورزشی، واحد اهواز، دانشگاه آزاد اسلامی، اهواز، ایران

²گروه زیست شناسی، واحد اهواز، دانشگاه آزاد اسلامی، اهواز، ایران

³گروه زیست شناسی، واحد ایذه، دانشگاه آزاد اسلامی، ایذه، ایران

چکیده

با افزایش سن برخی عملکردهای سیستم عصبی از جمله حافظه اجتنابی تضعیف می‏شود. اثرات مفید ورزش بر نوروژنز، افزایش سیناپس­های نورونی، درمان اختلالات روانی، کمک به بهبود جراحات مغزی و پیشگیری از بیماری­های نورودژنراتیو به اثبات رسیده است. از گیاهانی که در طب سنتی به اثرات ضد دردی آن اشاره شده لیموترش است؛ بنابراین در تحقیق حاضر تأثیر چهار هفته مصرف اسانس لیمو و تمرین شنا بر میزان حافظه و درد در موش سوری نر بررسی گردید. بدین منظور 40 سر موش سوری نر با وزن 5 ± 40 گرم مورد مطالعه قرار گرفت. موش ها به طور تصادفی به 4 گروه شامل کنترل، گروه شنا، گروه دریافت کننده اسانس لیموترش و گروه تمرین شنا + مصرف اسانس­ لیموترش تقسیم شدند. تمرین شنا شامل چهار هفته شنا در آب به مدت 30 دقیقه در هر جلسه و پنج جلسه در هفته بود و اسانس لیمو 50 میلی­گرم بر کیلوگرم به روش گاواژ تجویز گردید. جهت ارزیابی حافظه اجتنابی از دستگاه شاتل باکس و با استفاده از تست تیل فیلک، میزان آستانه درد مورد سنجش قرار گرفت. نتایج نشان داد اسانس لیموترش و تمرین شنا باعث کاهش معنادار احساس درد شده است (001/0p <). همچنین مصرف توأم اسانس لیمو و تمرین شنا سبب افزایش میزان حافظه در موش سوری نر می‏شود (001/0p <). تمرین هوازی، به ویژه شنا، اثر مثبت بر تثبیت حافظه و کاهش آستانه درد داشته است. احتمالاً مصرف اسانس لیمو به‌دلیل وجود آنتی اکسیدان‏های  ‏قوی می‌تواند احساس درد را کاهش دهد و حافظه اجتنابی را بهبود ببخشد.

کلیدواژه‌ها

اسانس لیمو؛ تمرین شنا؛ حافظه؛ درد؛ موش سوری نر بالغ

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