Cadmium chloride: a simple and efficient catalyst for the synthesis of 1,4-dihydropyridine (Hantzsch pyridines)

International Journal of Industrial Chemistry

دوره 3، شماره 1، اسفند 2012، صفحه 119-123

نوع مقاله: research article

شناسه دیجیتال (DOI): https://doi.org/10.1186/2228-5547-3-18

نویسندگان

Yekkirala Venkateswarlu؛ Sudhagani Ramesh Kumar؛ Panugati Leelavathi^*

Department of Chemistry, University College for Women, Koti, Osmania University, Hyderabad, 500095, India

چکیده

1,4-Dihydropyridine synthesis has been carried out using cadmium chloride as a catalyst. This protocol is applicable to a variety of aldehydes with β-ketoester and ammonium acetate to afford the corresponding Hantzsch pyridines in excellent yields. This multicomponent condensation took place very smoothly in acetonitrile reflux.

کلیدواژه‌ها

Aldehydes؛ Diketones؛ NH4OAc؛ CdCl2؛ 1؛ 4-dihydropyridine