The effect of acid/cellulose ratio on the quality of Cellulose Nanocrystal (CNC) suspension

Journal of Nanoanalysis

مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 03 اسفند 1400

نوع مقاله: Original Research Paper

شناسه دیجیتال (DOI): 10.22034/jna.2022.1938787.1270

نویسندگان

Nasrin Shahmiri¹؛ Nahid Hassanzadeh Nemati^{* 2}؛ Ahmad Ramazani Saadatabadi³؛ Massoud Seifi⁴

¹Department of biomedical engineering, Islamic Azad University , Science and Research branch, Tehran, Iran

²Department of biomedical engineering, Science and Research branch, Islamic Azad University, Tehran, Iran

³Department of Chemical & Petroleum Engineering, Sharif University of Technology, Tehran, Iran

⁴Department of Orthodontics, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran

چکیده

Cellulose nanocrystals are promising materials for application in biomedicine, pharmaceutical and food industry. There are various methods for CNC synthesis, but acid hydrolysis is the most common one. The optimization of acid hydrolysis process is still in progress. In the present study, different CNC suspensions were prepared to find out the more efficient acid ratio for CNC production. Whatman #1 filter paper was hydrolyzed via 64 wt% sulfuric acid at acid-to-paper ratio of 10:1 mL/g, 20:1 mL/g, 30:1 mL/g, and 40:1 mL/g. The synthesized CNCs were characterized by DLS, ELS and AFM. The suspensions with acid/cellulose ratio of 20:1 mL/g & 30:1 mL/g resulted in CNCs with more negative surface charge and uniform size. They also represented chiral nematic phase and regular self-organization after layer by layer deposition. It was found that the higher acid-to-paper ratio does not necessarily produce the high quality CNCs. Since the suspension that was prepared at acid/cellulose ratio of 40:1 mL/g had lower negative charge. The size and surface charge of CNCs are highly dependent to acid hydrolysis parameters and ultimately affect their behavior in nano-composites. In spite of many published papers around CNC synthesis by acid hydrolysis, there are still some details that must be addressed and investigated more to prepare the most efficient and applicable CNCs.

کلیدواژه‌ها

Cellulose Nanocrystal؛ Acid hydrolysis؛ Acid-to-cellulose ratio؛ Dynamic Light Scattering؛ Atomic Force Microscopy