One pot synthesis of conjugated chalcone-quinoxalines using an organocatalyst under ultrasonic mediation

Journal of Chemical Reactivity and Synthesis

دوره 11، شماره 4، اسفند 2021، صفحه 264-270   

نوع مقاله: Research Article

نویسنده

Kiana Darvishi^*

Department of chemistry, Takestan Branch, Islamic Azad University, Takestan, Iran

چکیده

Ultrasonic irradiation was effectively used for the synthesis of one pot chalcon-quinoxaline derivatives with high efficiency and short time. The products are obtained by mixing parahydroxy acetophenone and various aldehydes or parahydroxy benzaldehyde with different ketones and then adding 2,6-dichloroquinoxaline, in the presence of catalytic amounts of pyrrolidine as a organocatalyst and DMF as a solvent. These conjugated chalcon-quinoxaline derivatives have been shown to have good anticancer activity.
 

کلیدواژه‌ها

Ultrasonic mediation؛ Organocatalysts؛ Chalcone؛ Quinoxaline؛ Chalcon-quinoxaline