Selective and facile Synthesis of 2-Aminothiophenes Using Na2CaP2O7 as base Nano-Catalyst

Journal of Chemical Reactivity and Synthesis

دوره 12، شماره 1، خرداد 2022، صفحه 18-28   

نوع مقاله: Research Article

نویسندگان

Iman Khosravi^{* 1}؛ Elham Rastegar¹؛ Melika Eftekhar¹؛ Farid Moeinpour²

¹Department of Chemistry, Qeshm Branch, Islamic Azad University, Qeshm, Iran.

²Department of Chemistry, Bandar Abbas Branch, Islamic Azad University, Bandar Abbas, Iran

چکیده

In the study we reported synthesis of 2-aminothiophene derivatives in pure water using nano-structured Na₂CaP₂O₇. Our results indicated that this heterogeneous catalyst performed good selectivity and catalytic activity in the synthesis of substituted 2- aminothiophene through Gewald reaction in water. The noticeable benefits of this procedure rely on several factors including: a simple method, mildness conditions, short time of reaction, operational simplicity and low cost.

کلیدواژه‌ها

2-Aminothiophenes؛ Gewald reaction؛ nanocatalyst؛ Na2CaP2O7