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Preliminary Design of a Pressurized Liquid Extraction Unit for Phytochemicals Extraction | ||
Journal of Applied Chemical Research | ||
دوره 16، شماره 3، مهر 2022، صفحه 20-34 اصل مقاله (302 K) | ||
نوع مقاله: Original Article | ||
نویسندگان | ||
Aazam Sasani؛ Abbas Rashidi* | ||
Department of Chemical Engineering, Faculty of Technology and Engineering, University of Mazandaran | ||
چکیده | ||
In the present research, a Pressurized Liquid Extraction (PLE) unit has been preliminarily designed to extract bioactive compounds from medicinal plants. The design steps included: 1) Developing design baseswith general information about the process; 2) Preparing a concept processflow sheet in which the unit operation type, the required equipment, the main input and output flows and the flows related to the utilities are shown; 3) Determining the operational mode of the process; 4) Determining the type of equipment; and 5) Doing calculations and balancing energy and process materials. In this design, 500 kg of dried chopped plant and a combination of ethanol and water as solvent were used as input materials to the extractor. A batch mode is considered for the extraction operation and a continuous mode is considered for concentration operation. Unit operations were designed based on a fixed-bed extractor, and subsidiary equipment required were determined according to the desired conditions for the process also, falling film evaporator is used to concentrate the extract. By determining the flows, balancing the materials and energy, and doing the process-related calculations, the Process Flow Diagram (PFD) was finally obtained. | ||
کلیدواژهها | ||
Bioactive Compounds؛ Pressurized Liquid Extraction (PLE)؛ Preliminary Design؛ Medicinal Plants | ||
مراجع | ||
[1]. J.Azmir, I.S.M.Zaidul, M.M.Rahman, K.M.Sharif, A.Mohamed, F.Sahena, M.H.A.Jahurul, K.Ghafoor, N.A.N.Norulaini, A.K.M.Omar, J. Food Eng., 117(4), 426 (2013). [2]. M. Selvamuthukumaran, J. Shi, Food Qual. Saf., 1(1), 61 (2017). [3]. M.B. Soquetta, L.D.M. Terra, C.P. Bastos, CyTAJ. Food, 16(1), 400 (2018). [4]. K. Ameer, H.M. Shahbaz, J.H. Kwon, Compr. Rev. Food Sci. Food Saf., 16(2), 295 (2017). [5]. Y.-F. Shang, K. Hyun Cha, E. Ha Lee, C.-H. Pan, B.-H. Um, Free Radicals Antioxid., 6(1), 64 (2015). [6]. Z.Y. Ju, L.R. Howard, J. Agric. Food. Chem., 51(18), 5207 (2003). [7]. A.P.D.F. Machado, J.L. Pasquel-Reátegui, G.F. Barbero, J. Martínez, Food Res. Int., 77, 675 (2015). [8]. L. Howard, N.Pandjaitan, J. Food Sci., 73(3), C151 (2008). [9]. S. Erdogan, B. Ates, G. Durmaz, I. Yilmaz, T. Seckin, Food Chem. Toxicol., 49(7), 1592 (2011). [10]. Y. Jiang, S.P. Li, H.T. Chang, Y.T. Wang, P.F. Tu, J. Chromatogr. A, 1108(2), 268 (2006). [11]. Z.A. Syahariza, A.E. Torkamani, H.M. Norziah, W.A.K. Mahmood, P. Juliano, Int. J. Food Sci. Technol., 52(2), 480 (2017). [12]. L. Foan, V. Simon, J. Chromatogr. A, 1256, 22 (2012). [13]. A.D. Sousa, A.I.V. Maia, T.H.S. Rodrigues, K.M. Canuto, P.R.V. Ribeiro, R. de C.A. Pereira, R.F. Vieira, E.S. de Brito,Ind. Crops Prod., 79, 91 (2016). [14]. M.A. Rostagno, M. Palma, C.G. Barroso, Anal. Chim. Acta, 522(2), 169 (2004). [15]. J. Hu, Z. Guo, M. Glasius, K. Kristensen, L. Xiao, X. Xu, J. Chromatogr. A, 1218(34), 5765 (2011). [16]. J.L. Xu, T.J. Kim, J.-K. Kim, Y. Choi, Food Chem., 281, 261 (2019). [17]. G. Zgórka, Talanta, 79(1), 46 (2009). [18]. D.L. Luthria, J. Funct. Foods, 4(4), 842 (2012). [19]. D.L. Luthria, Food Chem., 107(2), 745 (2008). [20]. Y. Xu, F. Cai, Z. Yu, L. Zhang, X. Li, Y. Yang, G. Liu,Food Chem., 194, 650 (2016). [21]. S. Mukhopadhyay, D.L.Luthria, R.J. Robbins, J. Sci. Food Agric., 86(1), 156 (2006). [22]. H. Wu, M. Chen, Y. Fan, F. Elsebaei, Y. Zhu, Talanta, 88, 222 (2012). [23]. D.T. Santos, P.C.Veggi, M.A.A.Meireles, J. Food Eng., 108(3), 444 (2012). [24]. M. Søltoft, J.H. Christensen, J. Nielsen, P. Knuthsen, Talanta, 80(1), 269 (2009). [25]. A.H.Zaibunnisa, S.Norashikin, S.Mamot, H.Osman, LWT Food Sci. Technol., 42(1), 233 (2009). [26]. R.M. Alonso-Salces, A.Barranco, E.Corta, L.A.Berrueta, B. Gallo, F. Vicente,Talanta, 65(3), 654 (2005). [27]. A. Mustafa, C. Turner, Anal. Chim. Acta, 703(1), 8 (2011). [28]. M.S. Peters, K.D.Timmerhaus, R.E. West, Plant design and economics for chemical engineers, McGraw-Hill, New York (2003). [29]. B.E. Richter, B.A. Jones, J.L. Ezzell, N.L. Porter, N.Avdalovic, C.Pohl,Anal. Chem., 68(6), 1033 (1996). [30]. A. Sae-Yun, C. Ovatlarnporn, A. Itharat, R. Wiwattanapatapee, J. Chromatogr. A, 1125(2), 172 (2006). [31]. S. Koo, K. Cha, D. Song, D. Chung, C. Pan,J. Appl. Phycol., 24(4), 725 (2012). [32]T.L.Miron, M. Plaza, G.Bahrim, E. Ibáñez, M. Herrero,J. Chromatogr. A, 1218(30), 4918 (2011). [33]. Y.F. Shang, S.M. Kim, B.-H. Um, Food Chem., 154, 164 (2014). [34]. R.B. Carl, Rules of Thumb for Chemical Engineers, Gulf Publishing Company, USA (1998). [35]. E.E. Ludwig, Applied Process Design for Chemical and Petrochemical Plants: Volume 2, Gulf Professional Publishing, USA (1997). [36]. C. Pronyk, G. Mazza, J. Food Eng., 95(2), 215 (2009). [37]. R. Turton, R.C. Bailie, W.B. Whiting, J.A. Shaeiwitz, D. Bhattacharyya, Analysis, Synthesis and Design of Chemical Processes. Pearson Education, USA (2008). [38]. S. Hall, Rules of Thumb for Chemical Engineers. Butterworth-Heinemann, USA (2017). [39]. M.N. Shatla, M. El Hady, Storage Tanks-Selection of Type, Design Code and Tank Sizing. International conference of chemical engineering; Cairo (Egypt) (2004). [40]. W. Tipasri, T.Wongwuttanasatian, Energy Procedia, 156, 254 (2019). [41]. W.B. Glover, Chem. Eng. Prog., 100(12), 26 (2004). [42]. G.Saravacos, A.E.Kostaropoulos, Handbook of food processing equipment, Springer, Switzerland (2002). [43]. H. Chen, Factors affecting heat transfer in the falling film evaporator. A thesis presented in partial fulfillment of the requirements for the degree of Master of Technology in Food Technology at Massey University. Massey University (1992). [44]. Z.I. Stefanov, Fundamental modeling and control of falling film evaporators. PhD Thesis in Chemical Engineering. Texas Tech University (2004). [45]. A. Prakash, C. Patil, S.Vinodhini, A.Panneerselvam, V.D. Rajeswari, Engineering Approach in Beverage Industry, in Engineering Tools in the Beverage Industry, Elsevier (2019). [46]. E.S. Ong, S.M. Len, J. Chromatogr. Sci., 42(4), 211 (2004). [47]. E.S. Ong, S.M. Len, Anal.Chim. Acta, 482(1), 81 (2003). [48]. E.S. Ong, J. Sep. Sci., 25(13), 825 (2002). [49]. N.Y. Qin, F.Q. Yang, Y.T. Wang, S.P. Li, J. Pharm. Biomed. Anal., 43(2), 486 (2007). [50]. I.C.N. Debien, R. Vardanega, D.T. Santos, M.A.A. Meireles, Sep. Sci. Technol., 50(11), 1647 (2015). [51]. R.M. Alonso-Salces, E. Korta, A. Barranco, L.A. Berrueta, B. Gallo, F. Vicente, J. Agric. Food Chem., 49(8), 3761 (2001). [52]. B. Benthin, H.Danz, M. Hamburger, J.Chromatogr. A, 837(1-2), 211 (1999). [53]. E.-S. Ong, S.-O. Woo, Y.-L. Yong, J. Chromatogr. A, 904(1), 57 (2000). [54]. A.P. da Fonseca Machado, C.A. Rezende, R.A. Rodrigues, G.F. Barbero, P. de Tarso Vieira e Rosa, J. Martínez, Powder Technol., 340, 553 (2018). [55]. A.G. da Silva Carvalho, M.T. da Costa Machado, V.M. da Silva, A. Sartoratto, R.A.F. Rodrigues, M.D. Hubinger, Powder Technol., 294, 421 (2016). [56]. Y.R.R.S. Rezende, J.P. Nogueira, N.J.F.C.Narain, Food Chem., 254, 281(2018). [57]. E.Eroğlu, İ.Tontul, A.Topuz, J. Food Process. Preserv., 42(6), e13643 (2018). [58]. M.E. Sormoli, T.A.G.Langrish, Innovative Food Sci. Emerg. Technol., 37(A), 27 (2016). [59]. E. L. doCarmo, R.A.R. Teodoro, P.H.C. Félix, R.V. de BarrosFernandes, É. R. deOliveira, T.R.L.A. Veiga, S. V. Borges, D.A. Botrel, Food Chem., 249, 51 (2018). [60]. M.C.R. Salas, H.J.C.Velásquez, J.H.G. Gonzalez, Powder Technol., 321, 163 (2017). [61]. C. Yamashita, M.M.S. Chung, C. dos Santos, C.R.M. Mayer, I.C.F. Moraes, I.G. Branco, LWT, 84, 256 (2017). [62]. L.T.Chaul, E.C.Conceição, M.T.F.Bara, J.R.Paula, R.O.Couto, Revista Brasileira de Farmacognosia, 27(2), 236 (2017). [63]. T. Kuppan, Heat Exchanger Design Handbook, Marcel Dekker, Inc (2000). [64]. M. Nitsche, R.O.Gbadamosi, Heat Exchanger Design Guide: A Practical Guide for Planning, Selecting and Designing Shell and Tube Exchangers. Butterworth-Heinemann (2015). [65]. H.S. Lee, Thermal Design: Heat Sinks, Thermoelectrics, Heat Pipes, Compact Heat Exchangers, and Solar Cells, John Wiley & Sons (2010). [66]. G. Towler, R. Sinnott, Chemical Engineering Design: Principles, Practice and Economics of Plant and Process Design. Elsevier (2012). [67]. S. Rodríguez-Rojo, Antioxidants, 10(10), 1568 (2021). [68]. Z. Mrkonjic, D. Rakic, M. Kaplan, N. Teslic, Z. Zekovic, B. Pavlic, Molecules, 26, 2548 (2021). | ||
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