Synthesis and evaluation of antibacterial properties of green copper oxide nanoparticles from Hypericum perforatum plant extract and Marrubium Vulgare

Journal of Nanoanalysis

مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 03 خرداد 1401

نوع مقاله: Original Research Paper

شناسه دیجیتال (DOI): 10.22034/jna.2022.1951530.1291

نویسندگان

Ashkan Farazin^{* 1}؛ Shirin Kavezadeh²

¹Department of Solid Mechanics, Mechanical Engineering University of Kashan, Kashan, Iran

²Department of Electrical Engineering, University of Isfahan, Iran, P.O. Box 81746-73441

چکیده

In the present study, copper oxide nanoparticles were synthesized using Hypericum perforatum plant extract from the Malpican family and Marrubium Vulgare plant from the mint family. Since it is believed that the antioxidants in the plant reduce the reduction of metal ions to nanoparticles as reducing agents, these two plants were tested for their antioxidant properties by the free radical scavenging method, and the IC50 quantity was measured. Hypericum perforatum plant with IC50 equivalent to 0.413 had more antioxidant content than Marrubium Vulgare plant with IC50 equivalent to 1.562, so it was superior in the process of green synthesis. The properties of the synthesized nanoparticles were analyzed using X-ray diffraction (XRD), Scanning electron microscope (SEM), and Ultraviolet-visible (UV-Visible). The presence of a metal-oxygen bond was confirmed by Fourier-transform infrared spectroscopy (FTIR). X-ray energy diffraction spectra showed the purity of the synthesized nanoparticles. The synthesized nanoparticles were observed with spherical morphology and size distribution of 30 to 40 nm and with uniform size distribution. The results of the XRD spectrum showed that pH adjustment did not affect the synthesis of copper oxide nanoparticles. The nanoparticles synthesized against the two bacteria used in this present study did not show significant antibacterial properties compared to industrial antibiotics.

کلیدواژه‌ها

Marrubium Vulgare؛ Hypericum perforatum؛ Scanning electron microscope؛ Antibacterial properties؛ Industrial antibiotics