Morphological, phytochemical, and pharmacological investigation of Black Turmeric (Curcuma caesia Roxb.)

Journal of Medicinal Herbs, "J. Med Herb" (Formerly known as Journal of Herbal Drugs or J. Herb Drug)

دوره 13، شماره 2، آبان 2022، صفحه 1-6   

نوع مقاله: Review article

شناسه دیجیتال (DOI): 10.30495/medherb.2022.693885

نویسندگان

Sandeep Pandey^{* 1}؛ Shweta Pandey²؛ Monika Mishra²؛ Pooja Tiwari²

¹Center for Botany, School of Environmental Biology, APS University, Rewa, India.

²Botany Centre, Faculty of Environmental Biology, APS University, Rewa, India.

چکیده

Background & Aim: Curcuma caesia Roxb., commonly known as “Black turmeric” is a perennial rhizomatous critically endangered herb available in Northeast, Central, and Southern India. The plant possesses various medicinal properties and remains an untouched plant among researchers and growers.
Experimental:  In the current review keywords including black turmeric and medicinal properties, black turmeric and phytochemical, black turmeric and pharmacological application were searched in scientific websites such as PubMed, ResearchGate, and Google Scholar regarding plant description, distribution, chemical composition, and pharmacological investigation of black turmeric (Curcuma caesia Roxb.)
Results:  The plant with bioactive compounds in form of carotenoids, flavonoids, saponins, tannins, phenolics, terpenoids, coumarins, anthraquinones, etc. possess antioxidant, anti-cancer, anti-asthmatic, smooth muscle relaxant, anxiolytic, bronchodilating, anti-convulsant, CNS depressant, locomotor depressant, anthelmintic, anti-bacterial anti-fungal, and anti-mutagenic activities. The potentiality of the rhizome as an antiviral agent against coronavirus has also been justified and under trial.
Recommended applications/industries:  This review focuses on the description, phytochemical, and pharmacological investigation of the herb to explore its potentiality as an important medicinal plant with special emphasis on its preservation and cultivation among the growers.

کلیدواژه‌ها

Black turmeric؛ Phytochemical؛ Pharmacology

مراجع

Achour, S., Chebaibi, M., Essabouni, H., Bourhia, M., Ouahmane, L., Salamatullah, A.M., Aboul-Soud, M.A.M. and Giesy, J.P. 2022. Ethnobotanical Study of Medicinal Plants Used as Therapeutic Agents to Manage Diseases of Humans. Evidence-Based Complementary and Alternative Medicine, 2022, 1-8.

Al-Amin, M., Eltayeb, N.M., Khairuddean, M. and Salhimi, S.M. 2021. Bioactive chemical constituents from Curcuma caesia Roxb. rhizomes and inhibitory effect of curcuzederone on the migration of triple-negative breast cancer cell line MDA-MB-231. Natural Product Research, 35(18): 3166-3170.

Baghel, S.S., Baghel, R.S., Sharma, K. and Sikarwar, I. 2013. Pharmacological activities of Curcuma caesia. International Journal of Green Pharmacy, 7: 1-5.

Borah, S., Sarkar, P., Sharma, H.K. 2021. Analysing Curcuma caesia fractions and essential oil for neuroprotective potential against anxiety, depression, and amnesia. 3 Biotech, 11(5):240.

Borah, A., Kumar, D., Paw, M., Begum, T. and Lal, M. 2020. A review on ethnobotany and promising pharmacological aspects of an endangered medicinal plant, Curcuma caesia Roxb. Turkish Journal of Botany, 44: 205-213.

Chaturvedi, M., Rani, R., Sharma, D. and Yadav, J.P. 2021. Comparison of Curcuma Caesia extracts for bioactive metabolite composition, antioxidant and antimicrobial potential. Natural Product Research, 35(18): 3131-3135.

Das, S., Mondal, P. and Zaman, M.K. 2013. Curcuma caesiaRoxb. and it’s medicinal uses: A review.International Journal of Research in Pharmacy and Chemistry, 3(2): 370-375.

Dennis, V.J. 2021. Black Turmeric (Curcuma caesia Roxb): A High Value Medicinal Herb. Just Agriculture, 2(2): 1-4.

Devi, H. P. andMazumder, P. B. 2016. Methanolic extract of Curcuma caesia Roxb. prevents the toxicity caused by cyclophosphamide to bone marrow cells, liver and kidney of mice. Pharmacognosy Research, 8(1): 43–49.

Devi, H. P., Mazumder, P. B. and Devi, L. P. 2015. Antioxidant and antimutagenic activity of Curcuma caesia Roxb. rhizome extracts. Toxicology Reports, 2: 423–428.

Dewangan M.K., Dwivedi, C., Sivna, P.L., Rao S.P., Yadav R., Chandrakar,K., Singh S.S. and Sinha, D. 2014. Medicinal value of Curcuma cassia Roxb: An overview. Critical Review in Pharmaceutical Sciences, 3(4): 1-9.

Donipati, P. and Sreeramulu, S. H. 2015. Preliminary phytochemical screening of Curcuma caesia. International Journal of Current Microbiology and Applied Sciences, 4(11): 30-34.

Fatt, L.C., Rahman, N. W. A., Aziz, M.A.A. and Isa, K.M. 2021. Identification of the chemical constituents of Curcuma caesia (Black Turmeric) hydrosol extracted by hhydro-distillation method. IOP Conference Series: Earth and Environmental Science 765, 012025.

Grover, M., Shah, K., Khullar, G., Gupta, J. and Behl, T. 2019. Investigation of the utility of Curcuma caesia in the treatment of diabetic neuropathy. Journal of Pharmacy and Pharmacology, 71(5): 725–732.

Hadem, K. L., Sharan, R. N. and Kma, L. 2014. Inhibitory potential of methanolic extracts of Aristolochiatagala and Curcuma caesia on hepatocellular carcinoma induced by diethylnitrosamine in BALB/c mice. Journal of Carcinogenesis, 13: 7-11.

Hadem, K. L., Sharan, R. N. and Kma, L. 2015. Phytochemicals of Aristolochiatagala and Curcuma caesia exert anticancer effect by tumor necrosis factor-α-mediated decrease in nuclear factor kappaB binding activity. Journal of Basic and Clinical Pharmacy, 7(1): 1–11.

Kalita, V., Pegu, P. and Chetia, P. 2019. Phytochemical screening and evaluation of antioxidant, anti-microbial andanti-inflammatory activity of Curcuma caesia. International Journal of Pharmaceutical Science and Research, 10 (2):846-855.

Karim A., Singh, I., Khan, M.W. and Chourasia, R. 2017. Anthelmintic activity of Curcuma caesiaRoxb rhizome in Indian adult earthworm. European Journal of Biomedical and Pharmaceutical Sciences, 4(5): 289-292.

Karmakar, I., Dolai, N., Suresh Kumar, R.B., Kar, B., Roy S.N. and Haldar P.K. 2013. Antitumor activity and antioxidant property of Curcuma caesia against Ehrlich’s ascites carcinoma bearing mice. Pharmaceutical Biology, 51(6): 753-759. 

Kataki, C. and Bhattacharjee, M. 2020. An overview on medicinal uses of exiguous plant Curcuma caesia Roxb. International Journal of Pharmaceutical Sciences Review and Research, 63(1): 2: 4-7.

Mahato, D. and Sharma, H.P. 2018. Kali Haldi, an ethnomedicinal plant of Jharkhand state-A review. International Journal of Traditional Knowledge, 17(2): 322-326.

Majeed, A., Majeed, M., Thajuddin, N., Arumugam, S., Ali, F., Beede, K., Adams, S.J. andGnanamani, M. 2019. Bioconversion of curcumin into calebin-A by the endophytic fungus Ovatosporabrasiliensis EPE-10 MTCC 25236 associated with Curcuma caesia. AMB Expr 9, 79 (2019). https://doi.org/10.1186/s13568-019-0802-9

Mukunthan, K.S., Satyan, R.S. and Patel, T.N. 2017. Pharmacological evaluation of phytochemicals from South Indian Black Turmeric (Curcuma caesia Roxb.) to target cancer apoptosis. Journal of Ethnopharmacology, 209: 82-90.

Pakkirisamy, M., Kalakandan, S.K. and Ravichandran, K. 2017. Phytochemical screening, GC-MS, FT-IR analysis of methanolic extract of Curcuma caesia Roxb (Black Turmeric). Pharmacognosy Journal, 9(6): 952-956.

Paliwal, P., Pancholi, S.S. and Patel, R.K. 2011. Pharmacogenetic parameters for evaluation of the rhizomes of Curcuma caesia. Journal of Advanced Pharmaceutical Technology and Research, 2: 56-61.

Pandey, S., Kushwaha, G.R., Singh A. and Singh A. 2018. Chemical composition and medicinal uses of Anacyclus Pyrethrum Pharma Science Monitor, 9(1): 551-560.

Pandey, S., Kushwaha, S., Singh, S., Chaurasia, S. and Mishra, K. 2020. Phytochemical and pharmacological investigation of Cordia macleodii Hook. World Journal of Pharmaceutical and Life Sciences, 6(12): 216-220.

Pandey, S., Parmar, S., Shukla, M., Sharma, V., Dwivedi, A., Pandey, A. and Mishra, M. 2022. Phytochemical and pharmacological investigation of Cissus quadrangularis L. Herbal Medicines Journal, 7(2): 1-7.

Pathan, A.R. and Vandere, G.P. 2014. Ethnopharmacological evaluation of Curcuma caesia in management of Asthma. Inventi Rapid: Ethnopharmacology, 4: 1-4.

Pathan, A.R.,Vandere, G.P. and Sabu, M.2013. Curcuma caesia almost untouched drug: An updated ethnopharmacological review. Inventi Rapid: Planta Activa, 2013(4):1-4.

Paw, M., Gogoi, R., Sarma, N., Pandey, S.K., Borah, A., Begum, T. and Lal, M. 2020. Study of antioxidant, anti-inflammatory, genotoxicity, and antimicrobial activities and analysis of different constituents found in rhizome essential oil of Curcuma caesia Roxb., collected from North East India. Current Pharmaceutical Biotechnology, 21(5): 403-413.

Prasad, J., Satapathy, T., Verma, K., Sandey, L., Sinha, S., Verma, D., Sahu, D., Kaushik, S. and Dewangan, V.2021. Ethnomedicinal and pharmacological activity of Curcuma caesia. European Journal of Pharmaceutical and Medical Research, 8(5):226-232.

Rajkumari, S. and Sanatombi, K. 2017. Nutritional value, phytochemical composition, and biological activities of edible Curcuma species: A review. International Journal of Food Properties, 20:sup3, S2668-S2687. 

Ranemma, M. and Reddy, S. 2017. Phytochemical investigation study of Curcuma Caesia Roxb different geographical regions (Delhi and Orissa) of India. IOSR Journal of Biotechnology and Biochemistry, 3(1): 23-26.

Reenu, J., Azeez, S. and Bhageerathy, C. 2015. In vitro antioxidant potential in sequential extracts of Curcuma caesia Roxb. rhizomes. Indian Journal of Pharmaceutical Sciences, 77(1): 41–48.

Sahu, R. and Saxena, J. 2013. A brief review on medicinal value of Curcuma caecia. International Journalof Pharmacy and Life Sciences, 4(5): 2664-2666.

Sarma, I. and Deka, A.C. 2020. Conservation of Curcuma caesia Roxb.- A critically endangered species via in vitro plant regeneration from organogenic callus. Asian Journal of Conservation Biology, 9(1): 151-155.

Sawant, R.S. and Godghate, A.G. 2013. Qualitative phytochemical screening of rhizomes of Curcuma longa Linn. International Journal of Science, and Technology, 2(4): 634 – 641.

Sawant, S.B., Bihani, G., Mohod, S.M. and Bodhankar, S.L. 2014. Evaluation of analgesic and anti-inflammatory activity of methanolic extract of Curcuma caesia Roxb. rhizomes in laboratory animals. International Journal of Pharmacy and Pharmaceutical Sciences, 6(2):243-247.

Sharma, P., Bajaj, S., Fuloria, S., Porwal, O., Subramaniyan, V., Ozdemir, M., Meenakshi D. U., Kishore, N. and Fuloria, N.K. 2021. Ethnomedicinala and pharmacological uses of Curcuma Caesia. Natural Volatiles and Essential Oils, 8(4): 14902-14910.

Umadevi, P., Manivannan, S., Fayad, A. M. and Shelvy, S. 2020. In silico analysis of phytochemicals as potential inhibitors of proteases involved in SARS-CoV-2 infection. Journal of Biomolecular Structure and Dynamics: 1–9.

Venugopal, A. 2017.Medicinal properties of black turmeric: A review. International Journal of Sciences: 1-4.

Yadav, M. and Saravanan, K.K. 2019. Phytochemical analysis and antioxidant potential of rhizome extracts of Curcuma amada Roxb and Curcuma caesia Roxb. Journal of Drug Delivery and Therapeutics, 9(5):123-126.