Trachyspermum copticum essential oil: an effective herbal and natural antimicrobial agent against human skin pathogenic bacteria

International Journal of Bio-Inorganic Hybrid Nanomaterials

دوره 10، شماره 4، دی 2021، صفحه 193-205   

نوع مقاله: Research Paper

چکیده

The toxicity, negative side effects, and antimicrobial resistance of synthetic drugs are noticeable. The essential oil has revived in recent decades with a branch of alternative medicine. The aim of this study was to investigate and compare the antimicrobial effect of essential oil of Carian copticum with Body perp disinfectant on human skin. The essential oil was extracted from Trachchipermum Carian copticum seeds and also different concentrations of 25, 50, 100, and 200 ppm of essential oils were prepared. To compare the antimicrobial effect of Carian copticum essential oil with Body prep disinfectant was performed by a qualitative plate well method and quantitative microdilution method. Initial screening before skin disinfection resulted in the isolation of 29 isolates of Staphylococcus epidermidis, 12 isolates of Staphylococcus saprophyticus, 2 isolates of Enterococcus faecalis, 14 isolates of Micrococcus spp, and 9 isolates of diphtheroid and a total of 66 isolates. According to the microdilution method, the highest MIC belonged to Staphylococcus epidermidis with code C5 at 200 ppm and the lowest MIC was related to Staphylococcus epidermidis with code K5 and was equal to 25 ppm. The findings of this study showed that the essential oil of Carian copticum seed, in comparison with disinfectants (Body prep) that have some side effects, was not only effective in controlling clinical skin bacteria, but also had a good shelf life in competition with Body Prep. The results of the present study showed that the essential seed oil of the Carian copticum plant was able to successfully control skin pathogenic bacteria.

کلیدواژه‌ها

Antibacterial activity؛ Essential oil؛ Microdilution method؛ Minimum Inihibitory Concentration (MIC)؛ Minimum Bactericidal Concentration (MBC)؛ Skin Bactria؛ Trachyspermum copticum