The Effect of Magnetic Nanoparticles on Dynamic Behavior of Aorta Artery with Atherosclerosis Under the Action of Pulsating Blood Velocity

Journal of Solid Mechanics

مقاله 6، دوره 14، شماره 4، اسفند 2022، صفحه 477-490   

نوع مقاله: Research Paper

شناسه دیجیتال (DOI): 10.22034/jsm.2021.1933470.1700

نویسندگان

M.R Motaghedifar¹؛ A Fakhar^{* 1}؛ H Tabatabaei¹؛ M Mazochi²

¹Department of Mechanical Engineering, Kashan Branch, Islamic Azad University, Kashan, Iran

²Department of Cardiology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran

چکیده

In this article, a biomechanical model is presented for dynamic instability behavior of aorta arteries with atherosclerosis conveying pulsating blood including pharmaceutical nanoparticles. Utilizing Mindlin theory of cylindrical shell, the aorta artery is simulated mathematically. The atherosclerosis is assumed symmetric with lipid tissue. The pharmaceutical nanoparticles are subjected to magnetic field for attract to the lipid tissue in artery. Applying energy method and numerical method of differential quadrature (DQ), the final equations are solved for obtaining the dynamic instability region (DIR). The DIR is curve of dynamic blood velocity with respect to artery frequency. The influences of various variables of magnetic field, magnetic nanoparticle’s volume percent, tissue, lipid’s height and length upon dynamic behavior of aorta artery are investigated. Based on the results, the existence of magnetic nanoparticle in the blood enhances the artery frequency and consequently can lead to better heart performance and reduce the risk of heart attack.

کلیدواژه‌ها

Aorta artery؛ Atherosclerosis؛ Pulsating blood flow؛ Pharmaceutical nanoparticles؛ Numerical method

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