اثرات اجرای تمرین هوازی و گاواژ عصاره دارچین بر بیان ژن آدیپونکتین در بافت های کبد و چربی موش های نر تغذیه شده با رژیم غذایی پرچرب

مجله پلاسما و نشانگرهای زیستی

دوره 15، شماره 4 - شماره پیاپی 60، آذر 1401، صفحه 97-117   

نوع مقاله: مقاله پژوهشی

نویسندگان

ماریا دهواری¹؛ عبدالعلی بنایی فر^{* 2}؛ سجاد ارشدی²؛ اردشیر ظفری³

¹داشجوی دکترای فیزیولوژی ورزشی دانشگاه آزاد اسلامی واحد تهران جنوب

²گروه فیزیولوژی ورزش, دانشکده تربیت بدنی و علوم ورزشی, واحد تهران جنوب, دانشگاه آزاد اسلامی, تهران, ایران.

³گروه تربیت بدنی و علوم ورزشی, دانشکده علوم انسانی و هنر, واحد زنجان, دانشگاه آزاد اسلامی, زنجان, ایران.

چکیده

زمینه و هدف: آدیپونکتین با خواص مشابه تمرین جذب گلوکز در عضله را افزایش و تولید گلوکز در کبد را کاهش می دهد. دارچین دارای خواص تعدیل کننده در برابر استرس اکسیداتیو، قند خون و چاقی است. بنابراین, با توجه به تاثیر تمرینات ورزشی بر بیان ژن آدیپونکتین، تاثیر رژیم های پرچرب در بروز چاقی و اثرات دارچین در کاهش وزن ، پژوهش حاضر در پی پاسخ به این پرسش است که آیا شش هفته تمرین هوازی و عصاره دارچین بر بیان ژن آدیپونکتین در بافت های چربی و کبد و توده این بافت ها در موش های نر تغذیه شده با رژیم غذایی پرچرب اثرات متفاوتی دارد.
مواد و روش ها: پژوهش حاضر در قالب یک طرح پژوهشی چند گروهی با گروه کنترل انجام شد. میانگین متغیرهای پژوهش در بین گروه ها با هدف تعیین تفاوت های بین گروهی، با استفاده از آزمون آنالیز واریانس یک طرفه و آزمون تکمیلی بونفرونی و آزمون های t مستقل و آنالیز واریانس دو راهه در سطح معنی داری 05/0 ≥ p برای کلیه آزمون ها مقایسه شدند.
نتایج: رژیم غذایی پرچرب باعث کاهش  بیان ژن آدیپونکتین در بافت های چربی و کبدو  وزن بدن و وزن بافت های چربی و کبد بود. اجرای تمرین هوازی به تنهایی, مصرف عصاره دارچین به تنهایی و تعامل تمرین هوازی و عصاره دارچین سبب تغییرات مطلوب بیان ژن آدیپونکتین در بافت های چربی و کبد و و وزن بافت های چربی و کبد نسبت به گروه رژیم غذایی پرچرب شد.
نتیجه گیری : به نظر می رسد جدای از اثرات مطلوب و پذیرفته شده فعالیت های بدنی و تمرینات ورزشی بر بافت چربی و کبد، شاید مصرف برخی مکمل های غذایی مانند عصاره دارچین همراه با تمرین ورزشی بتوانند با  اثرات مطلوب و مفید تمرینات هم افزایی داشته باشند.

کلیدواژه‌ها

تمرین ورزشی . آدیپونکتین . دارچین؛ کبد؛ غذای پرچرب

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