Catalyst-free synthesis of aminothiazole derivatives in water

Iranian Journal of Organic Chemistry

دوره 14، شماره 3 - شماره پیاپی 55، آبان 2022، صفحه 3421-3424   

نوع مقاله: Original Article

نویسندگان

Mahboubeh Ghasemian Dazmiri^* ؛ Narges Ghasemi؛ Annataj Noushin

چکیده

Functionalized aminothiazole are generated from the reaction of dimethyl acetylenedicarboxylate, benzoylisothiocyanates, primary amines, hydrazonoyl chloride and triphenylphosphine in water. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.

کلیدواژه‌ها

aminothiazole؛ Phosphonate؛ Primary amines؛ Phosphites؛ Activated acetylenic compound؛ Benzoylisothiocyanates