Synthesis and Characterization of Carbon Ceramic Composite Based on Molecularly Imprinted Polymer for Selective Absorption of Cloxacillin Antibiotic from Milk

The Iranian Journal of Textile Nano-bio Modification

مقاله 5، دوره 1، شماره 3، اسفند 2022، صفحه 63-83   

نوع مقاله: Original Article

شناسه دیجیتال (DOI): 10.30495/ijtnbm.2023.1972929.1013

نویسندگان

Vahid Mahmoudi^{* 1}؛ Saeid Jafari²

¹Department of Polymer and Textile Engineering, Yazd Branch, Islamic Azad University, Yazd, Iran

²Center for Growth of Technology, Knowledge based Nano Kimia Kavir Yazd Pharmaceutical co., Islamic Azad University, Yazd Branch, Yazd, IRAN

چکیده

With the emergence of the industrial age, the growing concern over environmental pollution has been to drug resistance in humans due to the use of antibiotics and their discharge in environment. The aim of this work was to synthesis of a carbon ceramic composite based on molecular imprinted polymers (MIP) particles via non-covalent procedure as selective adsorbent for removal of Cloxacillin (CLO) antibiotic from aqueous and biological media (MILK). The effect of operational parameters includes pH (3-10), contact time (1-120 min), MIP (0.1 – 5.0 %wt) and adsorbent dosage (0.1- 2.0 g/L) was studied for optimization of CLO removal condition. The synthesized MIP particles and fabricated carbon composites were characterized using scanning electron microscopy and nitrogen absorption/desorption (BET). The results showed that the removal efficiency was highest in neutral conditions and increased as amount of MIP particles increased. The optimum conditions for removal of CLO (94%) were determined at pH = 6.5, 87 minutes as contact time and the 1.6 g/L carbon composite contain 3.1 % wt MIP. The performance of the synthesized composites was evaluated for Cloxacillin removal from the milk sample. The performance of the MIP particles for the Cloxacillin removal of milk samples supplied from livestock showed that these adsorbents can help to effectively reduce the residues of drug contamination in dairy samples.

کلیدواژه‌ها

Molecularly Imprinted Polymer؛ carbon ceramic composite؛ Cloxacillin؛ Milk

مراجع

[1] J. Jeong, W. Song, W.J. Cooper, J. Jung and J. Greaves, "Degradation of tetracycline antibiotics: Mechanisms and kinetic studies for advanced oxidation/reduction processes" Chemosphere, Vol. 78, pp 533 –540, 2010.

[2] C. Turner, P. Turner, L. Po, N. Maner, A. De Zoysa and B. Afshar, "Group B streptococcal carriage, serotype distribution and antibiotic susceptibilities in pregnant women at the time of delivery in a refugee population on the Thai-Myanmar border" BMC Infect Dis, vol. 12, pp 34-45, 2012.

[3] M. Noori Sepehr, S. Mohebi, S. Abdlollahi Vahed and M. Zarrabi, "Removal of Tetracycline from Synthetic Solution by Natural LECA" J Environ Heal Eng, vol.1, pp. 301–311, 2014.

[4] E.S. Elmolla and M. Chaudhuri, "The feasibility of using combined TiO2 photocatalysis-SBR process for antibiotic wastewater treatment" Desalination, vol. 272, pp. 218–24, 2011.

[5] M.H. Khan, H. Bae and J.Y. Jung, "Tetracycline degradation by ozonation in the aqueous phase: Proposed degradation intermediates and pathway" J Hazard Mater, vol. 181, pp. 659–665, 2010.

[6] I.R. Bautitz and R.F.P. Nogueira, "Degradation of tetracycline by photo-Fenton process-Solar irradiation and matrix effects" J Photochem Photobiol A Chem, vol. 187, pp. 33–39, 2007.

[7] C. Wu, X. Liu, D. Wei, J. Fan and L. Wang. "Photosonochemical degradation of phenol in water", Water Res, vol. 35, pp 3927–3933, 2021.

[8] A.H. Mahvi, "Application of Ultrasonic Technology for Water and Wastewater Treatment", Iran J Publ Heal, vol 38, pp. 1–17, 2009.

[9] A.H. Mahvi, A. Maleki, R. Rezaee and M. Safari, "Reduction of humic substances in water by application of ultrasound waves and ultraviolet irradiation" J Environ Heal Sci Eng, vol. 6, pp. 233–240, 2009.

[10] A. H. Mahvi, F. Vaezi, M. Alimohamadi and A Mehrabitavana, "Use of Solar Radiation in Disinfection of Drinking Water for Non-Urban Areas" Journal-Mil-Med, vol. 7, pp. 331–336, 2006.

[11] Y. Chi, W. Geng, L. Zhao, X. Yan, Q. Yuan and N. Li, "Comprehensive study of mesoporous carbon functionalized with carboxylate groups and magnetic nanoparticles as a promising adsorbent", J Colloid Interface Sci, vol. 369, pp. 366–372, 2012.

[12] F. Tan, M. Liu and S. Ren, "Preparation of polydopamine-coated graphene oxide/Fe3O4 imprinted nanoparticles for selective removal of fluoroquinolone antibiotics in water", Sci Rep, vol. 7, pp. 5735-5743, 2017.

[13] D. Davoodi, M. Hassanzadeh-Khayyat, M. Asgharian Rezaei and S.A. Mohajeri, "Preparation, evaluation and application of diazinon imprinted polymers as the sorbent in molecularly imprinted solid-phase extraction and liquid chromatography analysis in cucumber and aqueous samples" Food Chem, vol. 158, pp. 421–428, 2014.

[14] S. Shojaei, N. Nasirizadeh, M. Entezam, M. Koosha and M. Azimzadeh, "An Electrochemical Nanosensor Based on Molecularly Imprinted Polymer (MIP) for Detection of Gallic Acid in Fruit Juices" Food Anal Methods, vol. 9, pp. 2721–2731, 2016.

[15] T. Esfandiyari, N. Nasirizadeh, M.H. Ehrampoosh and M. Tabatabaee, "Characterization and absorption studies of cationic dye on multi walled carbon nanotube–carbon ceramic composite" J Ind Eng Chem, vol. 46, pp 35-43, 2017.

[16] W. Krenkel and F. Reichert, "Design Objectives and Design Philosophies, Interphases and Interfaces in Fiber-Reinforced CMCs" Comprehensive Composite Materials II, pp. 1-18, 2018.

[17] W.K. Tan, H. Muto, G. Kawamura, Z. Lockman and A. Matsuda, "Nanomaterial Fabrication through the Modification of Sol–Gel Derived Coatings" Nanomaterials, vol. 11, no. 1, pp 181-193, 2021.

[18] S. Jafari, M. Dehghani and N. Nasirizadeh, "Developing a Highly Sensitive Electrochemical Sensor Using Thiourea-Imprinted Polymers Based on an MWCNT Modified Carbon Ceramic Electrode", J Electroanal Chem, vol. 802, pp 139–146, 2017.

[19] S. Jafari, M. Dehghani, N. Nasirizadeh and M. H. Baghersad. "Synthesis and Characterization of a Selective Adsorbent Based on Molecularly Imprinted Polymer for the Removal of Cloxacillin Antibiotic Residue from Milk" Int J Dairy Technol, vol. 72, no. 4, pp 505-514, 2019.

[20] L. Chen, S. Xu and J. Li, "Recent advances in molecular imprinting technology: Current status, challenges and highlighted applications" Chem Soc Rev, vol 40, pp 2922-2942, 2011.

[21] S. Jafari, M. Dehghani, N. Nasirizadeh, M.H. Baghersad and M. Azimzadeh, "Label-free electrochemical detection of Cloxacillin antibiotic in milk samples based on Molecularly Imprinted Polymer and graphene oxide-gold nanocomposite" Measurement, vol 145, pp 22–29, 2019.

[22] H. Zhang, "Molecularly imprinted nanoparticles for biomedical applications", Adv Mat, vol. 32, no. 3, 1806328, 2020. ‏

[23] T. Vaneckova, J. Bezdekova, G. Han, V. Adam and M. Vaculovicova, "Application of molecularly imprinted polymers as artificial receptors for imaging" Acta Biomater, vol. 101, pp 444-458, 2020.

[24] W.A. El-Said, M. E. El-Khouly, M. H. Ali, R. T. Rashad, E. A. Elshehy and A. S. Al-Bogami, "Synthesis of mesoporous silica-polymer composite for the chloridazon pesticide removal from aqueous media" J Environ Chem Eng, vol 6, no. 2, pp. 2214-2221, 2018.

[25] Y. Xiao, R. Xiao, J. Tang, Q. Zhu, X. Li and Y Xiong, "Preparation and adsorption properties of molecularly imprinted polymer via RAFT precipitation polymerization for selective removal of aristolochic acid I", Talanta, vol. 162, pp 415–422, 2017.

[26] B. Soledad-Rodríguez, P. Fernández-Hernando, R.M. Garcinuño-Martínez and J.S. Durand-Alegría. "Effective determination of ampicillin in cow milk using a molecularly imprinted polymer as sorbent for sample preconcentration", Food Chem, vol. 224, pp 432–438, 2017.

[27] L.F.C. Miranda, D.S. Domingues and M.E.C. Queiroz, "Selective solid-phase extraction using molecularly imprinted polymers for analysis of venlafaxine, O-desmethylvenlafaxine, and N-desmethylvenlafaxine in plasma samples by liquid chromatography–tandem mass spectrometry" J Chromatogr A, vol. 1458, pp 46–53, 2016.

[28] K. Du, Z. Luo, P. Guo, W. Tang, N. Wu and P. Zheng, "Preparation and evaluation of a molecularly imprinted sol-gel material as the solid-phase extraction adsorbents for the specific recognition of cloxacilloic acid in Cloxacillin", J Sep Sci, vol. 39, pp 483–489, 2016.

[29] Z. Li, L. Schulz, C. Ackley and N. Fenske, "Adsorption of tetracycline on kaolinite with pH-dependent surface charges" J Colloid Interface Sci, vol. 351, pp. 254–260, 2010.

[30] N. Wu, Z. Luo, Y. Ge, P. Guo, K. Du and W. Tang, "A novel surface molecularly imprinted polymer as the solid-phase extraction adsorbent for the selective determination of ampicillin sodium in milk and blood samples", J Pharm Anal, vol. 6, pp 157–164, 2016.

[31] B. Zhang, H. Zhang, X. Li, X. Lei, C. Li, D. Yin, X. Fan and Q. Zhang, " Synthesis of BSA/Fe3O4 magnetic composite microspheres for adsorption of antibiotics", Mater Sci Eng C, Vol. 33, no. 7, Pp. 4401-4408, 2013.

[32] M.H. Fekri, S.I. Mohamareh and M. Hosseini, "Green synthesis of activated carbon/Fe3O4 nanocomposite from flaxseed and its application as adsorbent and antibacterial agent", Chem Pa, Vol. 76, pp. 6767–6782, 2022.

[33] M. Zahoor, M. Wahab, S. M. Salman, A. Sohail, E. A. Ali and R. Ullah, "Removal of Doxycycline from Water using Dalbergia sissoo Waste Biomass Based Activated Carbon and Magnetic Oxide/Activated Bioinorganic Nanocomposite in Batch Adsorption and Adsorption/Membrane Hybrid Processes", Bioinorg Chem Appl, Vol. 2022, pp. 1-15, 2022.