Catalyst free synthesis of pyrrole derivatives using multicomponent reactions

Iranian Journal of Organic Chemistry

دوره 15، شماره 2 - شماره پیاپی 58، مرداد 2023، صفحه 3595-3599   

نوع مقاله: Original Article

شناسه دیجیتال (DOI): 10.30495/iranjoc.2023.704940

نویسندگان

Samanehsadat Sharifi^* ؛ Narjes Haeizadeh

چکیده

A convenient and efficient procedure for the synthesis of substituted pyrroles has been reported based on three component reactions of primary amines and activated acetylenic compounds in the presence of N-formylmorpholine as a green solvent. The above synthetic procedure offers rapid access to novel and diversely substituted pyrrole derivatives.

کلیدواژه‌ها

N-formylmorpholine؛ Primary amines؛ pyrrole؛ Three-component reaction؛ Green Chemistry