Effect of Protein Corona Formation on Photonic Response of Upconverting Nanoparticles

International Journal of Biophotonics and Biomedical Engineering

دوره 3، شماره 1، مهر 2023، صفحه 49-56   

نوع مقاله: Research article

شناسه دیجیتال (DOI): 10.30495/ijbbe.2023.1985468.1025

نویسندگان

Nahid Ghazyani¹؛ Mohammad Hossien Majles Ara^{* 2}

¹Faculty of Physics, Kharazmi University, Tehran, Iran

²1. Department of physics, Kharazmi University, Tehran, Iran. 2. Applied Sciences Research Center, Kharazmi University, Karaj, Iran.

چکیده

NaYF4:Yb,Er is one of the efficient and well-known upconverting materials which emit photoluminescence light at 545 nm and 660 nm under an excitation of 980 nm. In this study, up-conversion nanoparticles using thermal decomposition method have been synthesized and characterized and phase transition from organic to aquas by synthesis a SiO2 shell have done successfully. The results show that the nonlinearity response of NaYF4: Yb, Er@SiO2 is same as NaYF4: Yb, Er and SiO2 has no effect on emission peaks it means that these nanoparticles are suitable for biomedical applications. Since it is necessary to know the photoluminescent behavior of UCNPs@SiO2 particles, thereby the fluorescence properties of up-conversion nanoparticles with SiO2 shell have been investigated in PBS, normal and cancerous human blood plasma. The results indicate that UCNP@SiO2 can be applicable in biological medias for therapy and diagnostic.

کلیدواژه‌ها

Nonlinear photoresponse؛ Upconversion Nanoparticles؛ Protein Corona؛ Corona Formation؛ human blood plasma؛ near infrared

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