Antibacterial Effect of Bioceramic Root Canal Sealer (BioRootTM) Modified with Thymus Kotschyanus Boiss

International Journal of Industrial Chemistry

مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 08 اسفند 1401

نوع مقاله: research article

نویسندگان

Khalid Mohammed Sharif Zebari¹؛ Abdullkareem Ramazan AL-Mezory^{* 2}؛ Hadar Saaeed Faizy²

¹Department of Conservative Dentistry, College of Dentistry, University of Duhok, Iraq

²College of Agricultural Engineering Science, Duhok University, Iraq

چکیده

The present study aimed to evaluate the antibacterial efficacy of bioceramic root canal sealer modified with herbal extracts, because there are insufficient scientific reports that indicate the antibacterial effects of herbal extracts added to endodontic root canal sealers. The essential oils of the aerial parts of Thymus Kotschyanus Boiss were obtained by hydrodistillation (HD) method and analyzed by Gas Chromatography-Mass Spectrometry (GC/MS) Analysis, and the major compounds were carvacrol (53.61) and thymol (12.78). The herbal extracts were added in different percentages to BioRootTM root canal sealer to know the effective concentration against the E.faecalis bacteria by placing into the Agar base, and the zones of inhibitions were measured. The groups were assessed as AHplus (control), BioRootTM, (BioRootTM+Thymus Kotschyanus Boiss) exp. Material (1-4)%, exp. material (1-2)%, exp. material (1-1)% and for evaluating the antibacterial activity the Agar Diffusion Test(ADT) was used. The AHplus (control) exhibited the largest inhibition zone 10.05 (0.99)mm, followed by Exp. material (1-1)% 7.82(0.77)mm, Exp. material (1-2)% 4.96 (0.60)mm, while the least inhibition zone was found in BioRootTM 4.39 (0.55)mm and exp. material (1-4)% was 4.36 (0.59)mm. Using ANOVA one-way test, there was a statistically significant difference of inhibition zone among root canal sealers. Based on results, statistical analysis and observation of the AHplus sealer and exp. Material (1-1)% had higher antibacterial effects than BioRootTM sealer, so the oil of Thymus Kotschyanus Boiss can be added as one of the components of root canal sealer, but farther research is needed before recommending it as sealers.

کلیدواژه‌ها

Thymus Kotschyanus Boiss؛ BioRootTM؛ AHplus؛ Agar Diffusion Test؛ Antibacterial activity