Evaluating drug Susceptibility of fungal species isolated from caught ants in Babol teaching Hospitals

International Journal of Molecular and Clinical Microbiology

دوره 14، شماره 1، مهر 2024، صفحه 2020-2026   

نوع مقاله: Research Article

شناسه دیجیتال (DOI): 10.22034/ijmcm.2024.710038

نویسندگان

Azadeh Zabihzadeh Amiri¹؛ Jalal Jafarzade²؛ Saeid Mahdavi Omran³؛ Mojtaba Taghizade Armaki⁴؛ Ali Heidarpour⁵؛ Amin Ghanbari⁶؛ Firoozeh Kermani⁴؛ Mohsen Karami^{* 4}

¹Faculty of Medical Sciences, Babol University of Medical Sciences, Babol, Iran

²Master of Medical Mycology, Faculty of Medical Sciences, Babol University of Medical Sciences, Babol, Iran

³Professor of Medical Mycology, Department of Medical Mycology and Parasitology, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

⁴Assistant Professor, Department of Parasitology and Mycology, Faculty of Medicine, Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran

⁵Master of Entomology, Faculty of Health, Faculty of Medical Sciences, Babol University of Medical Sciences, Babol, Iran

⁶School of medicine, Tehran University of Medical Sciences, Tehran, Iran

چکیده

Considering the role of ants as potential carriers of a wide range of fungal agents, including Aspergillus spp. and Candida spp. as well as the increasing incidence of treatment-resistant hospital fungal infections, the antifungal susceptibility of fungal isolated from the surfaces of ants caught from teaching hospitals of Babol city were evaluated. In the present experimental study, 46 fungal isolates including 15 strains of Aspergillus niger, 15 strains of Aspergillus flavus, 11 strains of Aspergillus fumigatus and 5 strains of Penicillium spp. were cultured on PDA medium and drug susceptibility to psoconazole, isavoconazole, itraconazole, loliconazole and voriconazole was determined according to CLSI (M238-A2) guidelines. The best antifungal effect was related to loliconazole, itraconazole and isaconazole on isolates of Aspergillus niger, Aspergillus fumigatus and Aspergillus flavus, respectively and posaconazole showed the weakest antifungal effect against to the studied isolates. Our knowledge regarding the level of sensitivity or resistance of fungal species with the source of hospital ants can highlight the role of these insects as carriers of hospital infections and also demonstrate the need for a regular preventive programmer to control these insects in different hospitalized areas.

کلیدواژه‌ها

Ant؛ Antifungal؛ Babol؛ Aspergillus؛ Fungi