Comparison the Prevalence of Candiduria in Diabetes and non-diabetic Patient’s: A case study

International Journal of Molecular and Clinical Microbiology

دوره 14، شماره 2، اسفند 2024، صفحه 2130-2136   

نوع مقاله: Research Article

شناسه دیجیتال (DOI): 10.22034/ijmcm.2024.710246

نویسندگان

Bahman Fouladi¹؛ Mohammad Foroozandeh Moghaddam²؛ Abdolahad Nabiolahi³؛ Nasser Keikha^{* 4}

¹1. Department of Parasitology and Mycology, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran.

²Student Research Committee, Zabol University of Medical Sciences, Zabol, Iran.

³Assistant Professor of Medical Librarianship and Information Sciences, Department of Medical library and Information Science, School of Allied Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Iran.

⁴Infectious Diseases and Tropical Medicine Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran.

چکیده

Opportunistic fungal infection is one of the most common causes of death and complications in immunocompromised patients. Candiduria is a general term for the presence of Candida spp. in urine. Diabetes Mellitus is considered one of the predisposing factors for Candida urinary tract infections. The aimed of this study was to compare the prevalence of Candiduria in diabetes and non-diabetic patient’s. By designing a case-control study, 90 diabetic patients referred to the clinic of Amir al-Momenin hospital during six months period were included in the case group and 90 non-diabetic patient’s was placed in the control group. A midstream urine sample was taken from each patient, after confirming the presence of yeast agents from all patient samples using the direct examination, culture was done on CROMagar candida medium. Out of 90 patients in the case group, 17 were diagnosed with candiduria. The frequency of candiduria in this group was reported to be 18.9%, the highest frequency was Candida albicans (12.2%), followed by C. glabrata (5.6) and C. parapseliosis (1.1). Also, in the control group, 2 people were diagnosed with candiduria. The surveys displayed that the prevalence of candiduria in diabetic patients was significantly higher compare to non-diabetics. In addition, there was a significant relationship between the prevalence of candiduria with C. albicans and non-albicans Candida in diabetic patients with predisposing factors such as uncontrolled blood sugar, and use of broad-spectrum antibiotics were observed. In conclusion candiduiria significantly more common in diabetic patients with uncontrolled Blood sugar and broad-spectrum antibiotic usage.

کلیدواژه‌ها

Candiduria؛ Diabetes Mellitus؛ Candida albicans؛ Epidemics؛ Hospital