Composition, Antioxidant and Antimicrobial Activities of Hexanic Extract from Prunus armeniaca L. Kernel from North-West Iran.

Journal of Pharmaceutical & Health Sciences

مقاله 8، دوره 2، شماره 3، شهریور 2014، صفحه 129-136   

نوع مقاله: Original Article

چکیده

Chemical characteristics, fatty acid composition, antioxidant and antimicrobial activities of
Prunus armeniaca kernel oil were evaluated in this study. The hexane extracts of kernel of P.
armeniaca, which were collected from northwestern Iran, were obtained by Soxhlet apparatus.
The fatty acids were derived to methyl esters and determined by gas chromatography/flame
ionization detector (GC/FID) and gas chromatography/mass spectrometry (GC/MS) systems.
The oil from kernel extract contained ω-6 (51.6%). The other main components were hexadecanoic
acid (palmitic acid) (23.0%), octadecanoic acid (stearic acid) (10.6%) and 9-hexadecenoic
acid (2.7%). Hexane extract of kernels from P. armeniaca detected as an important source of ω-6
compound. The antioxidant activity of the extract was evaluated by 1, 1-diphenyl-2-picrylhydrazyl
(DPPH) method. The results indicate that hexane extract from P. armeniaca kernels
possess considerable antioxidant activity. The IC50 values in the DPPH assay was 165μg/
mL. The antimicrobial activity of the extract was determined against some Gram-positive and
Gram-negative bacteria (Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, S.
epidermidis, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae), as well as
three fungi (Candida albicans, Saccharomyces cerevisiae and Aspergillus niger). The bioassay
showed that the oil exhibited moderate antimicrobial activity. This study reveals that the hexanic
extract from kernel of this fruit is attractive sources of ω-6.

کلیدواژه‌ها

Prunus armeniaca؛ Rosaceae؛ Kernel؛ ω- 6؛ fatty acid؛ Antioxidant Activity؛ Antimicrobial Activity