Boron trifluoride etherate; highly efficient catalyst for synthesis of tert-butylamides via modified Ritter reaction in solvent free condition

Journal of the Iranian Chemical Research

مقاله 4، دوره 5، شماره 1، خرداد 2012، صفحه 19-22   

نویسندگان

Masoud Mokhtary^{* 1}؛ Faranak Najafizadeh²

¹Department of Chemistry, Rasht Branch, Islamic Azad University, PO Box 41325-3516, Rasht, IRAN

²Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, PO Box 678, Amol, IRAN

چکیده

Highly efficient method for the preparation of N-tert-butyl amides by reaction of nitriles with tertbutylacetate
is described using boron trifluoride etherate in solvent free condition. Selective amidation of
benzonitrile in the presence of acetonitrile was also achieved.

کلیدواژه‌ها

Modified Ritter reaction؛ Boron trifluoride etherate؛ Nitriles؛ tert-Butylacetate, N- tert- Butyl amides

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