A Novel, Heterogeneous Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine Derivatives Under Solvent-Free Conditions

Journal of Chemical Reactivity and Synthesis

مقاله 1، دوره 2، شماره 2، مرداد 2012، صفحه 1-7   

نوع مقاله: Research Article

نویسندگان

Tayebeh Sanaeishoar^* ؛ Mitra Saremi

Department of Chemistry, College of Science, Khouzestan Science and Research Branch, Islamic Azad University, Ahvaz, Iran

چکیده

An efficient and environmental-friendly synthetic route to 1,8-dioxodecahydroacridines derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas catalyst under solvent-free conditions. The present approach offersseveral advantages such as short reaction times, easy isolation and purification of product, and safe, non-toxic, recyclable and economic use of catalyst.

کلیدواژه‌ها

Hantzsch؛ Solvent-free؛ One-pot synthesis؛ 1؛ 8-Dioxohexahydroacridine؛ Multicomponent