Investigation into the regioisomeric composition of some fused tetrazoles

Journal of Chemical Reactivity and Synthesis

مقاله 3، دوره 2، شماره 2، مرداد 2012، صفحه 13-21   

نوع مقاله: Research Article

نویسندگان

Paria Nasehi؛ Omid Baravaye؛ Sanaz Hafezi Birgani؛ Mohsen Nikpour^*

Departmentof Chemistry, School of Sciences, Islamic Azad University, Ahvaz Branch, Ahvaz

چکیده

Treatment of 7-chloro-1-phenylpyrimido[4,5-e][1,3,4]thiadiazines with hydrazine in boiling ethanol gave corresponding7-hydrazinyl derivatives. Diazotization of the latter compounds acheived a mixture of 5H-tetrazolo[1',5':1,2]pyrimido[4,5-e][1,3,4]thiadiazine and 9H-tetrazolo[5',1':2,3]pyrimido[4,5-e][1,3,4]thiadiazines. Ratio of these two group of products determined by ¹HNMR studies and no significant preference was observed for their formation. Efforts for separation of the products were unsuccessful and its reason is discussed.

کلیدواژه‌ها

7-chloro-1-phenylpyrimido[4؛ 5e][1؛ 4]thiadiazines؛ 7-hydrazinyl-1-phenylpyrimido[4؛ 4]thiadiazin؛ 5H-tetrazolo[1'؛ 5':1؛ 2]pyrimido[4؛ 9H-tetrazolo[5'؛ 1':2؛ 3]pyrimido[4؛ 5-e][1؛ 3؛ 4]thiadiazine؛ 1HNMR study؛ diazotization؛ tetrazole-azide tautomerism